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Identification of key miRNAs in papillary thyroid carcinoma based on data mining and bioinformatics methods

期刊: BIOMEDICAL REPORTS, 2020; 12 (1)

MicroRNAs (miRNAs) are a class of short (approximately 22 nucleotides), non-coding and endogenous RNA molecules that play pivotal roles in the occurre......

Intranasal injection of recombinant human erythropoietin improves cognitive and visual impairments in chronic cerebral ischemia rats

期刊: BIOMEDICAL REPORTS, 2020; 13 (5)

The present study aimed to study the protective effect of intranasally delivered recombinant human erythropoietin (rhEPO) on cognitive and visual impa......

Effects of varying intensities of heat stress on neuropeptide Y and proopiomelanocortin mRNA expression in rats

期刊: BIOMEDICAL REPORTS, 2020; 13 (5)

The aim of the present study was to investigate the effects of varying intensities of heat stress on the mRNA expression levels of neuropeptide Y (NPY......

Serum-deprivation leads to activation-like changes in primary microglia and BV-2 cells but not astrocytes

期刊: BIOMEDICAL REPORTS, 2020; 13 (5)

The aim of the present study was to determine the effect of serum deprivation on primary microglia, BV-2 cells and primary astrocytes. Cell morphology......

Neuroprotective effects of the aerial parts of Polygala tenuifolia Willd extract on scopolamine-induced learning and memory impairments in mice

期刊: BIOMEDICAL REPORTS, 2020; 13 (5)

Alzheimer's disease is a common neurodegenerative disease characterized by progressive cognitive dysfunction and behavioral impairment. Aerial parts o......

Endometrial cancer combined with polycystic ovary syndrome in 9 women under 40-years old: A case report

期刊: BIOMEDICAL REPORTS, 2020; 13 (5)

The aim of the present study was to discuss the clinicopathological characteristics of endometrial carcinoma in young females with polycystic ovary sy......

Serum parathyroid hormone levels in patients with chronic right heart failure

期刊: BIOMEDICAL REPORTS, 2020; 12 (2)

Parathyroid hormone (PTH) is a novel cardiovascular biomarker which is particularly useful for detection and assessment of heart failure (HF). However......

Diagnosis of a case of homozygous constitutional MMR-deficiency by the use of a gene-panel in a non-consanguineous family: A case report

期刊: BIOMEDICAL REPORTS, 2020; 12 (3)

Constitutional MMR-deficiency syndrome (CMMRD) is a rare but severe hereditary syndrome of pediatric cancer caused by bi-allelic pathogenic variants i......

Role of skeletal macrophages in fracture repair: A systematic review

期刊: BIOMEDICAL REPORTS, 2020; 13 (6)

In the field of bone research, the importance of the function of skeletal macrophages (sM Phi) and their crucial role in immune homeostasis and bone r......

Retrospective analysis of the effect of current clinical medications and clinicopathological factors on viral shedding in COVID-19 patients

期刊: BIOMEDICAL REPORTS, 2020; 13 (6)

The aim of the present study was to identify the risk factors associated with prolonged shedding in patients with coronavirus disease 2019 (COVID-19),......

Identification of four novel mutations in the <it><bold>COL4A5</it></bold> gene identified in Chinese patients with X-linked Alport syndrome

期刊: BIOMEDICAL REPORTS, 2020; 13 (2)

Alport syndrome (AS) is an inherited progressive nephropathy caused by mutations in one or two of the type IV collagen novel chains (alpha 3, alpha 4 ......

Total flavonoids of <it><bold>Selaginella pulvinata</it></bold> alleviates cognitive impairment in mice

期刊: BIOMEDICAL REPORTS, 2020; 13 (2)

Cognitive impairment (CI) refers to dysfunctional cognition, which encompasses a spectrum of disorders, ranging from mild cognitive impairment to deme......

Two-component signaling pathways modulate drug resistance of <bold>Staphylococcus aureus</bold>

期刊: BIOMEDICAL REPORTS, 2020; 13 (2)

As the issues surrounding antibiotic-resistant strains of Staphylococcus aureus (S. aureus) are becoming increasingly serious concerns, it is imperati......

<it><bold>Apocynum venetum</it></bold> leaf extract protects against H2O2-induced oxidative stress by increasing autophagy in PC12 cells

期刊: BIOMEDICAL REPORTS, 2020; 13 (2)

The effect of Apocynum venetum leaf extract (AVLE) on the nervous system has been widely studied, but its effect on injured neurons is not fully under......

Bioinformatics analysis shows that TOP2A functions as a key candidate gene in the progression of cervical cancer

期刊: BIOMEDICAL REPORTS, 2020; 13 (4)

Cervical cancer (CC) is one of the most prevalent types of cancer affecting females worldwide. However, the molecular mechanisms underlying the develo......

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