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Arsenic: A Global Environmental Challenge

期刊: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 61, 2021, 2021; 61 ()

Arsenic is a naturally occurring metalloid and one of the few metals that can be metabolized inside the human body. The pervasive presence of arsenic ......

Structural Basis for Allosteric Modulation of Class B G Protein-Coupled Receptors

期刊: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 60, 2020; 60 ()

Recent advances in our understanding of the structure and function of class B G protein-coupled receptors (GPCRs) provide multiple opportunities for t......

Levering Mechanically Activated Piezo Channels for Potential Pharmacological Intervention

期刊: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 60, 2020; 60 ()

The mechanically activated Piezo channels, including Piezol and Piezo2 in mammals, function as key mechanotransducers for converting mechanical force ......

Lung Cancer Heterogeneity and New Strategies for Drug Therapy

期刊: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, VOL 58, 2018; 58 ()

Lung cancer heterogeneity plays an important role in the development of drug resistance. Comprehensive molecular characterizations of lung cancer can ......

JIF:12.1

Oxidative Stress and Metabolism: A Mechanistic Insight for Glyphosate Toxicology

期刊: ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 2022; 62 ()

Glyphosate (GLYP) is a widely used pesticide; it is considered to be a safe herbicide for animals and humans because it targets 5-enolpyruvylshikimate......

JIF:12.629

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