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Immune checkpoint inhibitors for brain metastases in non-small-cell lung cancer: from rationale to clinical application

期刊: IMMUNOTHERAPY, 2021; 13 (12)

Brain metastases (BM) is common in non-small-cell lung cancer (NSCLC) patients. Immune checkpoint inhibitors (ICIs) have gradually become a routine tr......

Immunotherapy in psoriasis

期刊: IMMUNOTHERAPY, 2021; 13 (7)

Over the past two decades, a huge progress in the treatment of psoriasis was achieved by targeting the human cytokine network. At present, 11 biologic......

Cost-effectiveness analysis of ribociclib plus fulvestrant for hormone receptor-positive/human EGF receptor 2-negative breast cancer

期刊: IMMUNOTHERAPY, 2021; 13 (8)

Aim: To evaluate the cost-effectiveness of ribociclib plus fulvestrant versus fulvestrant in hormone receptor-positive/human EGF receptor 2-negative a......

Immunotherapy versus standard chemotherapy for treatment of extensive-stage small-cell lung cancer: a systematic review

期刊: IMMUNOTHERAPY, 2021; 13 (12)

Aim: We conducted a systematic review and network meta-analysis to evaluate the efficacy of immunotherapy versus chemotherapy to treat extensive-stage......

Identification and functional study of novel oligonucleotides: CpG Seq 13 and CpG Seq 19

期刊: IMMUNOTHERAPY, 2021; 13 (7)

Aim: This study explored new immunoadjuvants with stronger immune activity to enhance therapeutic effects against leukemia. Materials & methods: W......

Therapeutic cancer vaccine therapy for acute myeloid leukemia

期刊: IMMUNOTHERAPY, 2021; 13 (10)

Lay abstract Acute myeloid leukemia (AML) is the most common acute leukemia in adults with poor prognosis. Evidence has shown that the immune system c......

A case of pembrolizumab-induced fulminant Type 1 diabetes mellitus in breast cancer

期刊: IMMUNOTHERAPY, 2021; 13 (6)

Lay abstract Immunotherapy, which can stimulate the immune system to exert anti-tumor effects, has been reported to cause some side effects. Here, we ......

Immune-checkpoint inhibitors versus other systemic therapies in advanced head and neck cancer: a network meta-analysis

期刊: IMMUNOTHERAPY, 2021; 13 (6)

Aim: We assessed the efficiency of immune checkpoint inhibitors relative to other systemic therapies in previously treated recurrent/metastatic head a......

The safety and efficacy of immune-checkpoint inhibitors in patients with cancer and pre-existing autoimmune diseases

期刊: IMMUNOTHERAPY, 2021; 13 (6)

Objective: This study aims at investigating the safety and efficacy of immune-checkpoint inhibitors (ICIs) in patients with cancer and pre-existing au......

Efficacy and safety of chimeric antigen receptor T cell immunotherapy in B-cell non-Hodgkin lymphoma: a systematic review and meta-analysis

期刊: IMMUNOTHERAPY, 2021; 13 (4)

Aim: The aim was to evaluate the efficacy and safety of chimeric antigen receptor T (CAR-T) cell in B-cell non-Hodgkin lymphoma (B-NHL). Materials &am......

Aggravation of depigmentation for a non-small-cell lung cancer patient with pre-existing vitiligo using anti-programmed cell death-1 therapy: case report

期刊: IMMUNOTHERAPY, 2020; 12 (3)

Immune checkpoint inhibitors can enhance the antitumor activity of the immune system by mainly promoting CD8(+) T lymphocyte immune function. However,......

Economic burden of patients with advanced non-small-cell lung cancer receiving nivolumab versus chemotherapy in China

期刊: IMMUNOTHERAPY, 2020; 12 (4)

Aim: As new treatment patterns are gradually being used in patients with non-small-cell lung cancer, it is necessary to have a better understanding of......

Successful treatment of metastatic colorectal cancer with synchronous BRAF V600E mutation and dMMR with BGB-A317

期刊: IMMUNOTHERAPY, 2020; 12 (4)

Metastatic colorectal cancer with BRAF mutation is a type of highly invasive malignant tumor with poor prognosis and few treatment options. Here, we r......

Durable response to combination radiotherapy and immunotherapy in EP-resistant lung large-cell neuroendocrine carcinoma with B2M and STK11 mutations: a case report

期刊: IMMUNOTHERAPY, 2020; 12 (4)

Lung large-cell neuroendocrine carcinoma (LCNEC) is a rare tumor with poor prognosis. Despite the increasing prevalence of immune checkpoint inhibitor......

The characteristic of tumor immune microenvironment in pulmonary carcinosarcoma

期刊: IMMUNOTHERAPY, 2020; 12 (5)

Pulmonary carcinosarcoma (PCS) is a rare but aggressive neoplasm, due to late diagnosis and early metastasis. Surgery combined with radiotherapy is a ......

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