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Regulation of Electronic Properties of Metal Oxide Nanoparticles to Reveal Their Toxicity Mechanism and Safe-by-Design Approach

期刊: ADVANCED BIOLOGY, 2021; 5 (2)

Metal oxide (MO) nanoparticles (NPs) are widely applied to medicine, agriculture, industry, and other fields, however, their potential toxicity is oft......

Identification of Protein Direct Interactome with Genetic Code Expansion and Search Engine OpenUaa

期刊: ADVANCED BIOLOGY, 2021; 5 (3)

Protein crosslinks occur endogenously such as modifications by ubiquitin-like proteins for signaling, or exogenously through genetically encoded chemi......

Suppressive Myeloid Cells Shape the Tumor Immune Microenvironment

期刊: ADVANCED BIOLOGY, 2021; 5 (3)

Cancer is the outcome of the conflict between the host immune system and cancer cells. The crosstalk between immune cells and tumor cells within the t......

Advances in Targeted Therapy and Immunotherapy for Pancreatic Cancer

期刊: ADVANCED BIOLOGY, 2021; 5 (3)

Pancreatic cancer is a highly aggressive malignancy with an overall 5-year survival rate of <6% due to therapeutic resistance and late-stage diagno......

Interfacial Curvature as a Potential Index for Prognosis of Colon Adenocarcinoma

期刊: ADVANCED BIOLOGY, 2021; 5 (3)

Tumor invasion and metastasis are complex interfacial mechanical processes between the tumor and its surrounding tissue, with the interfacial curvatur......

Photothermally Activated Coacervate Model Protocells as Signal Transducers Endow Mammalian Cells with Light Sensitivity

期刊: ADVANCED BIOLOGY, 2021; 5 (8)

The development of a novel photothermally activated coacervate model protocell is reported as a signal transducer to endow mammalian cells with light ......

Lipid Metabolism in Ferroptosis

期刊: ADVANCED BIOLOGY, 2021; 5 (8)

Lipid metabolism is a complex biochemical process that participates in the regulation of cell survival and death. Ferroptosis is a form of iron-depend......

Injectable Mesenchymal Stem Cell-Laden Matrigel Microspheres for Endometrium Repair and Regeneration

期刊: ADVANCED BIOLOGY, 2021; 5 (8)

Endometrial injury and intrauterine adhesions are increasingly reported in recent years; however, treatment options remain limited. Intravenous inject......

Development of Host-Orthogonal Genetic Systems for Synthetic Biology

期刊: ADVANCED BIOLOGY, 2021; 5 (3)

The construction of a host-orthogonal genetic system can not only minimize the impact of host-specific nuances on fine-tuning of gene expression, but ......

Review of Stimulated Raman Scattering Microscopy Techniques and Applications in the Biosciences

期刊: ADVANCED BIOLOGY, 2021; 5 (1)

Stimulated Raman scattering (SRS) microscopy is a nonlinear optical imaging method for visualizing chemical content based on molecular vibrational bon......

Integrating Engineering, Automation, and Intelligence to Catalyze the Biomedical Translation of Organoids

期刊: ADVANCED BIOLOGY, 2021; 5 (8)

Organoid technology has developed at an impressive speed during the past decade. Still, organoids are not widely used in practical applications as exp......

Patient-Specific Organoid and Organ-on-a-Chip: 3D Cell-Culture Meets 3D Printing and Numerical Simulation

期刊: ADVANCED BIOLOGY, 2021; 5 (6)

The last few decades have witnessed diversified in vitro models to recapitulate the architecture and function of living organs or tissues and contribu......

Stress Response and Nutrient Homeostasis in Lettuce (Lactuca sativa) Exposed to Graphene Quantum Dots Are Modulated by Particle Surface Functionalization

期刊: ADVANCED BIOLOGY, 2021; 5 (4)

A 5-d germination assay and a 14-d hydroponic trial are performed to evaluate the impacts of graphene quantum dots (GQDs) on lettuce. Results show tha......

Hyaluronan-Mediated Motility Receptor Governs Chromosome Segregation by Regulating Microtubules Sliding Within the Bridging Fiber

期刊: ADVANCED BIOLOGY, 2021; 5 (6)

Accurate segregation of chromosomes during anaphase relies on the central spindle and its regulators. A newly raised concept of the central spindle, t......

Emulating Early Atherosclerosis in a Vascular Microphysiological System Using Branched Tissue-Engineered Blood Vessels

期刊: ADVANCED BIOLOGY, 2021; 5 (4)

Atherosclerosis begins with the accumulation of cholesterol-carrying lipoproteins on blood vessel walls and progresses to endothelial cell dysfunction......

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