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NR4A1 inhibits the epithelial-mesenchymal transition of hepatic stellate cells: Involvement of TGF-beta-Smad2/3/4-ZEB signaling

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

This study aimed to examine whether nuclear receptor 4a1 (NR4A1) is involved in inhibiting hepatic stellate cell (HSC) activation and liver fibrosis t......

JIF:1.008

Effects of soil treated fungicide fluopimomide on tomato (Solanum lycopersicum L.) disease control and plant growth

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Fluopimomide is a novel acid amide fungicide registered for the control of many plant pathogens. In the present study, the effects of soil-treated flu......

JIF:1.008

Metagenomic next-generation sequencing in diagnosing Pneumocystis jirovecii pneumonia: A case report

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

It remains a huge challenge for clinicians to diagnose Pneumocystis jirovecii pneumonia (PJP) by a conventional method, which leads to delay in diagno......

JIF:1.008

Calcifying nanoparticles initiate the calcification process of mesenchymal stem cells in vitro through the activation of the TGF-beta 1/Smad signaling pathway and promote the decay of echinococcosis

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

The role of the calcifying nanoparticles (CNPs) in the calcification process of the outer cyst wall in hepatic cystic echinococcosis (HCE) remains unk......

JIF:1.008

Aggravated renal fibrosis is positively associated with the activation of HMGB1-TLR2/4 signaling in STZ-induced diabetic mice

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Diabetic kidney dysfunction is closely associated with renal fibrosis. Although the suppression of fibrosis is crucial to attenuate kidney damage, the......

JIF:1.008

Characterization of intestinal microbiota and serum metabolites in patients with mild hepatic encephalopathy

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Mild micro-hepatic encephalopathy (MHE) is a severe complication of cirrhosis. At present, there are differences in the consistency of detection strat......

JIF:1.008

Study on the genetic damage caused by cadmium sulfide quantum dots in human lymphocytes

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Cadmium sulfide quantum dots (CdS QDs) are being developed for sensors, fluorescent probes, and other platforms and are attracting increasing attentio......

JIF:1.008

Selection and validation of reference genes for RT-qPCR analysis of different organs at various development stages in Caragana intermedia

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Reverse transcription quantitative PCR (RT-qPCR) is a technique widely used to investigate the expression of genes. An appropriate reference gene (RG)......

JIF:1.008

A novel association between Bmi-1 protein expression and the SUVmax obtained by F-18-FDG PET/CT in patients with gastric adenocarcinoma

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

This study aimed to examine B-cell-specific Moloney murine leukemia virus integration site 1 (Bmi-1) in gastric adenocarcinoma (GAC) and its associati......

JIF:1.008

Geometric basis of action potential of skeletal muscle cells and neurons

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Although we know something about single-cell neuromuscular junctions, it is still unclear how multiple skeletal muscle cells coordinate to complete in......

JIF:1.008

Continuous renal replacement therapy combined with double filtration plasmapheresis in the treatment of severe lupus complicated by serious bacterial infections in children: A case report

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

There are few reports available on the combination therapy of continuous renal replacement therapy (CRRT) and double filtration plasmapheresis (DFPP) ......

JIF:1.008

Bilateral dacryoadenitis in adult-onset Still's disease: A case report

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

We present an unusual case of bilateral dacryoadenitis in a middle-aged patient with adult-onset Still's disease (AOSD). We reviewed relevant clinical......

JIF:1.008

Analysis of genetic characteristics of 436 children with dysplasia and detailed analysis of rare karyotype

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Chromosomal abnormality is one of the important causes of dysplasia in children. However, due to regional and ethnic differences, the reported rates o......

JIF:1.008

Effects of the interaction of Notch and TLR4 pathways on inflammation and heart function in septic heart

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

We investigated the role of the interaction between the Notch and Toll-like receptor 4 (TLR4) pathways in septic myocardial injury. The sepsis model w......

JIF:1.008

Hepatoprotective role of peroxisome proliferator-activated receptor-alpha in non-cancerous hepatic tissues following transcatheter arterial embolization

期刊: OPEN LIFE SCIENCES, 2022; 17 (1)

Transcatheter arterial embolization (TAE) is a widely used technique in treating hepatic carcinoma but may cause liver injury in some cases. This stud......

JIF:1.008

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