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The use of sentinel skin islands for monitoring buried and semi-buried micro-vascular flaps. Part I: Summary and brief description of monitoring methods

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2021; 165 (2)

Micro-vascular flaps have been used for the repair of challenging defects for over 45 years.The risk of failure is reported to be around 5-10% which d......

The use of sentinel skin islands for monitoring buried and semi-buried micro-vascular flaps. Part II: Clinical application

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2021; 165 (2)

Despite the high success rate of micro-vascular flaps, anastomosis compromise occurs in 5-10% and that can lead to flap failure. Reliable monitoring o......

Preparation of PLGA microspheres loaded with 10-hydroxycamptothecin and arsenic trioxide and their treatment for rabbit hepatocellular carcinoma

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2021; 165 (1)

Objective. This study aims to study the preparation method of arsenic trioxide (As2O3) polylactic-co-glyconlic acid (PLGA) microspheres and 10-hydroxy......

Upregulation of miR150-5p in generalized myasthenia gravis patients is associated with decreased serum levels of IL-17 and increased serum levels of IL-10

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2020; 164 (1)

Background. MiR150-5p has been reported to be involved in generalized myasthenia gravis, in which different cytokines play critical roles. The regulat......

Protective effects of resveratrol on acute kidney injury in rats with sepsis

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2020; 164 (1)

Aim. To evaluate the protective effects of resveratrol on acute kidney injury (AKI) in septic rats. Methods. A septic rat model was established by cec......

Serum sphingosine negatively correlates with albumin predicting the risk of hepatocellular carcinoma

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2020; 164 (2)

Background. The roles of sphingosine in various cancers have not been fully investigated. Our aim was to identify the relationship between serum sphin......

Downregulation of CIP2A inhibits cancer cell proliferation and vascularization in renal clear cell carcinoma

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2020; 164 (2)

Background. CIP2A has been proved to play a role as an oncogene in various types of malignancies while its functionality in renal clear cell carcinoma......

Effects of dexmedetomidine versus remifentanil on mothers and neonates during cesarean section under general anesthesia

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2020; 164 (4)

Background and Aims. Dexmedetomidine and remifentanil use in obstetric general anesthesia is controversial. This study aimed to compare the effects of......

Bioinformatics analysis of genes associated with the patchy-type alopecia areata: CD2 may be a new therapeutic target

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2020; 164 (4)

Background. Alopecia areata (AA) is mainly a T cell-medicated autoimmune disease with non-scarring hair loss and limited treatment options. Of these, ......

A comparative study on the secretion of various cytokines by pulp stem cells at different passages and their neurogenic potential

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2022; 166 (2)

Aims. By measuring the extent of cytokines secreted by human dental pulp stem cells (hDPSCs) from passages 2 through 10, the optimal passage of hDPSCs......

JIF:1.025

Construction of the miRNA-mRNA regulatory network and analysis of hub genes in oral squamous cell carcinoma

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2022; 166 (3)

Background. Oral squamous cell carcinoma (OSCC) severely affects the quality of life and the 5-year survival rate is low. Exploring the potential miRN......

JIF:1.025

Association of CD103+T cell infiltration with overall survival in solid tumors of the digestive duct and its potential in anti-PD-1 treatment: A review and meta-analysis

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2022; 166 (2)

We looked into the most recent studies of digestive tumor patients and performed a meta-analysis to explore the association of CD103+ T cell infiltrat......

JIF:1.025

Imipenem and normal saline with cyclophosphamide have positive effects on the intestinal barrier in rats with sepsis

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2018; 162 (2)

Background. Sepsis is a life-threatening organ dysfunction caused the dysregulation of host inflammatory response and immunosuppression to infection E......

JIF:1.14

The effects of O-GlcNAc alteration on Alzheimer-like neurodegeneration in SK-N-SH cells

期刊: BIOMEDICAL PAPERS-OLOMOUC, 2018; 162 (3)

Background. O-GlcNAcylation is a highly dynamic post-translational modification that plays a key role in regulating phosphorylation of protein and cel......

JIF:1.14

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