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LARGE-SCALE INFERENCE OF CORRELATION AMONG MIXED-TYPE BIOLOGICAL TRAITS WITH PHYLOGENETIC MULTIVARIATE PROBIT MODELS

期刊: ANNALS OF APPLIED STATISTICS, 2021; 15 (1)

Inferring concerted changes among biological traits along an evolutionary history remains an important yet challenging problem. Besides adjusting for ......

RAPID DESIGN OF METAMATERIALS VIA MULTITARGET BAYESIAN OPTIMIZATION

期刊: ANNALS OF APPLIED STATISTICS, 2021; 15 (2)

Composed of a large number of subwavelength unit cells with designable geometries, metamaterials have been widely studied to achieve extraordinary adv......

SIMULTANEOUS INFERENCE OF PERIODS AND PERIOD-LUMINOSITY RELATIONS FOR MIRA VARIABLE STARS

期刊: ANNALS OF APPLIED STATISTICS, 2021; 15 (2)

The period-luminosity relation (PLR) of Mira variable stars is an important tool to determine astronomical distances. The common approach of estimatin......

AN EMPIRICAL BAYES CHANGE-POINT MODEL FOR TRANSCRIPTOME TIME-COURSE DATA

期刊: ANNALS OF APPLIED STATISTICS, 2021; 15 (1)

Time-course experiments are commonly conducted to capture temporal changes. It is generally of interest to detect if any changes happen over time, whi......

AN EFFICIENT AND COMPUTATIONALLY ROBUST STATISTICAL METHOD FOR ANALYZING CASE-CONTROL MOTHER-OFFSPRING PAIR GENETIC ASSOCIATION STUDIES

期刊: ANNALS OF APPLIED STATISTICS, 2020; 14 (2)

Case-control mother-offspring pair design has been widely adopted for studying early-life and women's pregnancy health. It allows assessment of pre- a......

EFFECTIVE MODEL CALIBRATION VIA SENSIBLE VARIABLE IDENTIFICATION AND ADJUSTMENT WITH APPLICATION TO COMPOSITE FUSELAGE SIMULATION

期刊: ANNALS OF APPLIED STATISTICS, 2020; 14 (4)

Estimation of model parameters of computer simulators, also known as calibration, is an important topic in many engineering applications. In this pape......

A COMPARISON OF PRINCIPAL COMPONENT METHODS BETWEEN MULTIPLE PHENOTYPE REGRESSION AND MULTIPLE SNP REGRESSION IN GENETIC ASSOCIATION STUDIES

期刊: ANNALS OF APPLIED STATISTICS, 2020; 14 (1)

Principal component analysis (PCA) is a popular method for dimension reduction in unsupervised multivariate analysis. However, existing ad hoc uses of......

FEATURE SELECTION FOR GENERALIZED VARYING COEFFICIENT MIXED-EFFECT MODELS WITH APPLICATION TO OBESITY GWAS

期刊: ANNALS OF APPLIED STATISTICS, 2020; 14 (1)

Motivated by an empirical analysis of data from a genome-wide association study on obesity, measured by the body mass index (BMI), we propose a two-st......

TFISHER: A POWERFUL TRUNCATION AND WEIGHTING PROCEDURE FOR COMBINING p-VALUES

期刊: ANNALS OF APPLIED STATISTICS, 2020; 14 (1)

The p-value combination approach is an important statistical strategy for testing global hypotheses with broad applications in signal detection, meta-......

SURFACE TEMPERATURE MONITORING IN LIVER PROCUREMENT VIA FUNCTIONAL VARIANCE CHANGE-POINT ANALYSIS

期刊: ANNALS OF APPLIED STATISTICS, 2020; 14 (1)

Liver procurement experiments with surface-temperature monitoring motivated Gao et al. (J. Amer. Statist. Assoc. 114 (2019) 773-781) to develop a vari......

COMMON AND INDIVIDUAL STRUCTURE OF BRAIN NETWORKS

期刊: ANNALS OF APPLIED STATISTICS, 2019; 13 (1)

This article focuses on the problem of studying shared-and individual-specific structure in replicated networks or graph-valued data. In particular, t......

JIF:1.66

RCRNORM: AN INTEGRATED SYSTEM OF RANDOM-COEFFICIENT HIERARCHICAL REGRESSION MODELS FOR NORMALIZING NANOSTRING NCOUNTER DATA

期刊: ANNALS OF APPLIED STATISTICS, 2019; 13 (3)

Formalin-fixed paraffin-embedded (FFPE) samples have great potential for biomarker discovery, retrospective studies and diagnosis or prognosis of dise......

JIF:1.66

ADJUSTMENT OF NONCONFOUNDING COVARIATES IN CASE-CONTROL GENETIC ASSOCIATION STUDIES

期刊: ANNALS OF APPLIED STATISTICS, 2018; 12 (1)

It has recently been reported that adjustment of nonconfounding covariates in case-control genetic association analyses may lead to decreased power wh......

JIF:1.66

VARIABLE SELECTION FOR ESTIMATING THE OPTIMAL TREATMENT REGIMES IN THE PRESENCE OF A LARGE NUMBER OF COVARIATES

期刊: ANNALS OF APPLIED STATISTICS, 2018; 12 (4)

Most existing methods for optimal treatment regimes, with few exceptions, focus on estimation and are not designed for variable selection with the obj......

JIF:1.66

NETWORK-BASED FEATURE SCREENING WITH APPLICATIONS TO GENOME DATA

期刊: ANNALS OF APPLIED STATISTICS, 2018; 12 (2)

Modern biological techniques have led to various types of data, which are often used to identify important biomarkers for certain diseases with approp......

JIF:1.66

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