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The Effect of Sildenafil Citrate on Poor Endometrium in Patients Undergoing Frozen-Thawed Embryo Transfer following Resection of Intrauterine Adhesions: A Retrospective Study

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (3)

Background: The recent studies have shown that sildenafil citrate can enhance estrogen-induced proliferation of the endometrium in infertile women. Ob......

Effect and Safety of Remifentanil Patient-Controlled Analgesia Compared with Epidural Analgesia in Labor: An Updated Meta-Analysis of Randomized Controlled Trials

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (3)

Purpose: The study was aimed to systematically assess the effect and safety of remifentanil patient-controlled analgesia (rPCA) versus epidural analge......

Tissue Transglutaminase Impairs HTR-8/SVneo Trophoblast Cell Invasion via the PI3K/AKT Signaling Pathway

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (3)

Objectives: The pathogenesis of preeclampsia (PE) is associated with impaired trophoblast invasion, which results in placental insufficiency. Our earl......

Serum Copper Level and Polycystic Ovarian Syndrome: A Meta-Analysis

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (3)

Introduction: The association of serum copper with polycystic ovarian syndrome (PCOS) has been studied for years, but no definite conclusion is drawn.......

Changes of Serum Sex Hormone-Binding Globulin, Homocysteine, and Hypersensitive CRP Levels during Pregnancy and Their Relationship with Gestational Diabetes Mellitus

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (1-2)

Background: Inflammatory response state is related to the pathogenesis of gestational diabetes mellitus (GDM). Objective: To investigate the changes o......

The Association between Maternal/Fetal Insulin Receptor Substrate 1 Gene Polymorphism rs1801278 and Gestational Diabetes Mellitus in a Chinese Population

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (1-2)

Objectives: Insulin receptor substrate 1 (IRS1) is a crucial factor in the insulin signaling pathway. IRS1 gene polymorphism rs1801278 in mothers has ......

Comparison of Insulin, Metformin, and Glyburide on Perinatal Complications of Gestational Diabetes Mellitus: A Systematic Review and Meta-Analysis

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (3)

Aim: This systematic and meta-analysis was conducted to evaluate the efficacy and safety of insulin, metformin, and glyburide on perinatal complicatio......

Effect of IL-15-Mediating IFN-gamma on HTR-8/SVneo Cells and a Preeclampsia Mouse Model Induced by Lipopolysaccharides

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, 2021; 86 (3)

Objective: Determine the effect of interleukin (IL)-15 on HTR-8/SVneo cells and a preeclampsia (PE) mouse model induced by LPS. Methods: Transwell and......

Maternal Myometrium Metabolomic Profiles in Labor: Preliminary Results

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, ; ()

Introduction: Parturition involves multiple complex metabolic processes that supply essential metabolites to facilitate fetal delivery. Little is know......

MicroRNA-301a Promotes Cell Proliferation and Resistance to Apoptosis through PTEN/PI3K/Akt Signaling Pathway in Human Ovarian Cancer

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, ; ()

Background: MicroRNAs are endogenous small noncoding RNAs, which play a critical role in regulating various biological and pathologic processes. Furth......

The Setup and Application of Reference Material in Sequencing-Based Noninvasive Prenatal Testing

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, ; ()

Introduction: The sequencing-based noninvasive prenatal testing (NIPT) has been successfully integrated into clinical practice and facilitated the ear......

Elevated Circulating Levels of Carnal ENST00000550337.1 Are Associated with Polycystic Ovary Syndrome in Chinese Women

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, ; ()

Objectives: Polycystic ovary syndrome (PCOS) is a common endocrine and metabolic disease. Some studies reported that the development of PCOS may be cl......

A New Concept for Central Wedge Resection in Labiaplasty

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, ; ()

Objective: The aim of the study was to develop a new concept for central wedge resection to improve surgical results. Currently, the most common posto......

Higher Levels of Triglyceride, Fatty Acid Translocase, and Toll-Like Receptor 4 and Lower Level of HDL-C in Pregnant Women with GDM and Their Close Correlation with Neonatal Weight

期刊: GYNECOLOGIC AND OBSTETRIC INVESTIGATION, ; ()

Objectives: In this study, we aimed to compare the levels of maternal blood lipids, placental and venous blood lipid transporters, and inflammatory fa......

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