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The RNA-binding protein Musashi2 governs osteoblast-adipocyte lineage commitment by suppressing PPAR gamma signaling

期刊: BONE RESEARCH, 2022; 10 (1)

Osteoporosis caused by aging is characterized by reduced bone mass and accumulated adipocytes in the bone marrow cavity. How the balance between osteo......

JIF:11.588

Progress in osteoarthritis research by the National Natural Science Foundation of China

期刊: BONE RESEARCH, 2022; 10 (1)

Osteoarthritis (OA) in China is gradually becoming an important scientific research area that has had a significant impact on research and development......

JIF:11.588

Strontium-incorporated bioceramic scaffolds for enhanced osteoporosis bone regeneration

期刊: BONE RESEARCH, 2022; 10 (1)

The restoration of bone defects caused by osteoporosis remains a challenge for surgeons. Strontium ranelate has been applied in preventative treatment......

JIF:11.588

Current understanding of osteoarthritis pathogenesis and relevant new approaches

期刊: BONE RESEARCH, 2022; 10 (1)

Osteoarthritis (OA) is the most common degenerative joint disease that causes painful swelling and permanent damage to the joints in the body. The mol......

JIF:11.588

A high-resolution route map reveals distinct stages of chondrocyte dedifferentiation for cartilage regeneration

期刊: BONE RESEARCH, 2022; 10 (1)

Articular cartilage damage is a universal health problem. Despite recent progress, chondrocyte dedifferentiation has severely compromised the clinical......

JIF:11.588

Progression in translational research on spinal cord injury based on microenvironment imbalance

期刊: BONE RESEARCH, 2022; 10 (1)

Spinal cord injury (SCI) leads to loss of motor and sensory function below the injury level and imposes a considerable burden on patients, families, a......

JIF:11.588

Generation of functional oligopeptides that promote osteogenesis based on unsupervised deep learning of protein IDRs

期刊: BONE RESEARCH, 2022; 10 (1)

Deep teaming (DL) is currently revolutionizing peptide drug development due to both computational advances and the substantial recent expansion of dig......

JIF:11.588

Prospects and challenges of dynamic DNA nanostructures in biomedical applications

期刊: BONE RESEARCH, 2022; 10 (1)

The physicochemical nature of DNA allows the assembly of highly predictable structures via several fabrication strategies, which have been applied to ......

JIF:11.588

Circular RNA circStag1 promotes bone regeneration by interacting with HuR

期刊: BONE RESEARCH, 2022; 10 (1)

Postmenopausal osteoporosis is a common bone metabolic disorder characterized by deterioration of the bone microarchitecture, leading to an increased ......

JIF:11.588

Ammonia promotes the proliferation of bone marrow-derived mesenchymal stem cells by regulating the Akt/mTOR/S6k pathway

期刊: BONE RESEARCH, 2022; 10 (1)

Ammonia plays an important role in cellular metabolism. However, ammonia is considered a toxic product. In bone marrow-derived mesenchymal stem cells,......

JIF:11.588

Computer vision-aided bioprinting for bone research

期刊: BONE RESEARCH, 2022; 10 (1)

Bioprinting is an emerging additive manufacturing technology that has enormous potential in bone implantation and repair. The insufficient accuracy of......

JIF:11.588

Toll-like receptor 9 deficiency induces osteoclastic bone loss via gut microbiota-associated systemic chronic inflammation

期刊: BONE RESEARCH, 2022; 10 (1)

Toll-like receptors (TLRs) play pivotal roles in inflammation and provide important links between the immune and skeletal systems. Although the activa......

JIF:11.588

Recent advances in smart stimuli-responsive biomaterials for bone therapeutics and regeneration

期刊: BONE RESEARCH, 2022; 10 (1)

Bone defects combined with tumors, infections, or other bone diseases are challenging in clinical practice. Autologous and allogeneic grafts are two m......

JIF:11.588

FABP4 secreted by M1-polarized macrophages promotes synovitis and angiogenesis to exacerbate rheumatoid arthritis

期刊: BONE RESEARCH, 2022; 10 (1)

Increasing evidence shows that adipokines play a vital role in the development of rheumatoid arthritis (RA). Fatty acid-binding protein 4 (FABP4), a n......

JIF:11.588

Construction of developmentally inspired periosteum-like tissue for bone regeneration

期刊: BONE RESEARCH, 2022; 10 (1)

The periosteum, a highly vascularized thin tissue, has excellent osteogenic and bone regenerative abilities. The generation of periosteum-mimicking ti......

JIF:11.588

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