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Extraction process and method validation for bioactive compounds from Citrus reticulata cv. Chachiensis: Application of response surface methodology and HPLC-DAD

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (3)

Citrus reticulata cv. Chachiensis, a traditional Chinese herb, has extensive medicinal and edible effects. 30,40,5,6,7,8-Hexamethoxyflavone (HM) and 5......

Antitumor chemical constituents of Toddalia asiatica (Linn) Lam root bark and its rational alternative medicinal parts by multivariate statistical analysis

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (2)

Toddalia asiatica (Linn) Lam (T. asiatica) as a traditional Miao medicine was investigated to find rational alternative medicinal parts for T. asiatic......

A rapid and sensitive High-Performance Liquid Chromatography-tandem Mass Spectrometry method for determining apremilast in beagle dog plasma and urine: Application in a pharmacokinetic study

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (2)

A rapid and sensitive High-Performance Liquid Chromatography-tandem Mass Spectrometry (HPLC/MS/MS) method for determining apremilast in beagle dog pla......

Rapid measurement of anticoagulant rodenticides in human blood and urine using online turbulent flow chromatography coupled with liquid chromatography-tandem mass spectrometry

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (4)

Anticoagulant rodenticides (ARs) are widely used to control rodents. A method based on online turbulent flow chromatography (TFC) combined with LC-MS/......

Development and validation of a rapid UHPLC-MS/MS method for the determination of fenofibric acid in human plasma: Application to a pharmacokinetic study of fenofibrate tablet in Chinese subjects

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (4)

An ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) method was developed to determine the fenofibric acid (FA) in h......

New conditions of HPLC analysis for separation and quantification of simple organic acids of tricarboxylic acid cycle in psoriasis

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (4)

Tricarboxylic acid cycle is an important pathway and the metabolites of tricarboxylic acid cycle, simple organic acids, play important roles in many p......

Determination of sarecycline by UPLC-MS/MS and its application to pharmacokinetic study in rats

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (3)

Sarecycline is a narrow-spectrum antibiotic for the treatment of acne, which is a chronic inflammatory disease of the hair follicle sebaceous glands. ......

A sweeping-micellar electrokinetic chromatography method for the detection of three chlorophenols in cosmetic samples

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (4)

A sweeping micellar electrokinetic chromatography (sweeping-MEKC) enrichment model was established for the determination of three chlorophenols (CPs) ......

Simultaneous determination of carbofuran and 3-hydroxycarbofuran in duck liver by an UPLC-MS/MS

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (4)

Carbofuran is a carbamate pesticide, a broad-spectrum, high-efficiency, low-residue, and highly toxic insecticide, acaricide, and nematicide, widely u......

Study on discrimination of different grades of rapeseed oil based on flavor fingerprint

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (3)

In this work, Gas chromatograph-Mass Spectrometry (GC-MS) combined with solid phase micro-extraction technology was used to analyze the difference of ......

Pharmacokinetics and bioavailability of liensinine in mouse blood by UPLC-MS/MS

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (4)

Liensinine is a bisbenzyltetrahydroisoquinoline alkaloid extracted from lotus (Nelumbo nucifera GAERTNER., Nelumbonaceae), especially in its embryo lo......

Analysis of gallic acid and ellagic acid in leaves of Elaeagnus angustifolia L. from different habitats and times in Xinjiang by HPLC with cluster analysis

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (2)

Objective: To determine the levels of gallic acid and ellagic acid by using high-performance liquid chromatography (HPLC) with R software hierarchical......

CF-PK-PD analysis of natural hemostatic compounds from Toddalia asiatica (Linn) Lam root bark in rats

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (3)

Natural hemostatic compounds from Toddalia asiatica (Linn) Lam (T. asiatica) root bark had been investigated by a novel strategy, chemical fingerprint......

Determination of ligustrazine in rat serum by polymer monolithic micro-extraction combined with ultra high performance liquid chromatography-tandem mass spectrometry

期刊: ACTA CHROMATOGRAPHICA, 2021; 33 (3)

This study focused on developing an effective and environmentally friendly method to measure ligustrazine in rat serum by using polymer monolith micro......

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