期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (7)
Humans are constantly exposed to formaldehyde (FA) of both exogenous and endogenous sources, and FA exposure is associated with the development of man......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 24 (8)
The relationship between human papillomavirus (HPV) and esophageal cancer (EC) has been controversial, which may be caused by the difference in geogra......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (6)
The ability of chemicals to enter the blood-brain barrier (BBB) is a key factor for central nervous system (CNS) drug development. Although many model......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (4)
Stroke is a significant cardiovascular disease that influences the health of human beings all over the world, especially the elderly population. It is......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (4)
Binimetinib is a selective MEK1/2 inhibitor, which is indicative of melanoma. We aimed to investigate the inhibitory effect of binimetinib on cytochro......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (1)
Diclofenac sodium (DFS), a nonsteroidal anti-inflammatory drug, is frequently used in ophthalmology, but it causes negative effects on corneas. The me......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (4)
Pyridinium aldoximes are best-known therapeutic antidotes used for clinical treatment of poisonings by organophosphorus nerve-agents and pesticides. R......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (6)
The influence of excessive metal-organic frameworks (MOFs) on the translation process was investigated in this study. Different concentrations and siz......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (6)
We previously demonstrated that apolipoprotein A-I (apoA-I), the major protein component of high-density lipoprotein (HDL), is an important target for......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (1)
Emerging evidence suggests that chronic exposure to aristolochic acids (AAs) is one of the etiological pathways leading to chronic kidney disease (CKD......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (5)
Triclosan (TCS) is a ubiquitous antimicrobial used in many daily consumer products. It has been reported to induce endocrine disrupting effects at low......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (6)
Perfluorotridecanoic acid (PFTrDA) is a long-chain (C13) perfluoroalkyl carboxylic acid. Here, we report the influence of PFTrDA exposure on the matur......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (7)
Cisplatin is a chemotherapeutic agent widely employed in the treatment of various solid tumors. However, its use is often restricted by acute kidney i......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 34 (6)
Labetalol hydrochloride (LHCl), an alpha- and beta-adrenoreceptor blocker, is widely used for the treatment of hypertension as well as angina pectoris......
期刊: CHEMICAL RESEARCH IN TOXICOLOGY, 2021; 24 (8)
Cytochrome P450 2C8 (CYP2C8) is a major drug-metabolizing enzyme in humans and is responsible for the metabolism of similar to 5% drugs in clinical us......