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Circ_0000735 enhances the proliferation, metastasis and glycolysis of non-small cell lung cancer by regulating the miR-635/FAM83F axis

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (3)

Background Circular RNA (circRNA) is considered to be an important regulator of cancer malignant progression, including non-small cell lung cancer (NS......

Hydrogen regulates the M1/M2 polarization of alveolar macrophages in a rat model of chronic obstructive pulmonary disease

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (7)

Objective Chronic obstructive pulmonary disease (COPD) is a respiratory disease with high morbidity and mortality worldwide, so far there is no ideal ......

Role of the Notch ligands Jagged1 and Delta4 in Th17/Treg immune imbalance in a mouse model of chronic asthma

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (6)

Purpose Asthma is associated with a T helper (Th)17/regulatory T (Treg) cells immune imbalance where the Notch signaling pathway contributes vitally. ......

The role of circTMOD3 in regulating LPS-induced acute inflammation and injury in human lung fibroblast WI-38 cells

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (7)

Background Circular RNAs (circRNAs) have been implicated in the molecular etiology of pediatric pneumonia. Here, we investigated the precise action of......

Comparison of properties of dust in alveolar of rats and the workplace

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (5)

Objectives The purpose of this study was to analyze the alpha-SiO2 content, composition, dispersion, morphology, and free radical content of dust betw......

ACTL6A promotes the growth in non-small cell lung cancer by regulating Hippo/Yap pathway

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (5)

Purpose: To delve into the related molecular mechanism of ACTL6A on non-small cell lung cancer (NSCLC) cell growth and apoptosis. Methods: Quantitativ......

Intermittent hypoxia: Friend or foe on endothelial repair in mouse model

期刊: EXPERIMENTAL LUNG RESEARCH, ; ()

Aim of the study: Obstructive sleep apnea, which is characterized by intermittent hypoxia (IH), is a common respiratory disease. The aim of the presen......

LncRNA CHRF promotes TGF-beta 1 induced EMT in alveolar epithelial cells by inhibiting miR-146a up-regulating L1CAM expression

期刊: EXPERIMENTAL LUNG RESEARCH, ; ()

Purpose Idiopathic pulmonary fibrosis (IPF) is a type of progressive lung fibrosis disease. The survival time of diagnosed IPF patients is often only ......

Effects of different concentrations of mesenchymal stem cells treatment on LPS-induced acute respiratory distress syndrome rat model

期刊: EXPERIMENTAL LUNG RESEARCH, ; ()

Purpose This study was prospectively designed to investigate the effects of different concentrations of mesenchymal stem cells treatment on respirator......

LncRNA NEAT1 promotes airway smooth muscle cell inflammation by activating the JAK3/STAT5 pathway through targeting of miR-139

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (4)

Background Asthma is a chronic inflammatory heterogeneous respiratory disease. Previous studies showed that the lncRNA NEAT1 (nuclear paraspeckle asse......

DLC1 inhibits lung adenocarcinoma cell proliferation, migration and invasion via regulating MAPK signaling pathway

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (4)

Lung adenocarcinoma (LUAD), one of the most common cancers, is a major threat to people's health due to its high mortality, and the survival of most p......

Silencing of long noncoding RNA H19 alleviates pulmonary injury, inflammation, and fibrosis of acute respiratory distress syndrome through regulating the microRNA-423-5p/FOXA1 axis

期刊: EXPERIMENTAL LUNG RESEARCH, 2021; 47 (4)

Purpose This study aimed to explore the regulatory effects and mechanisms of long noncoding RNA H19 (H19) on pulmonary injury, inflammation, and fibro......

Lef1 is transcriptionally activated by Klf4 and suppresses hyperoxia-induced alveolar epithelial cell injury

期刊: EXPERIMENTAL LUNG RESEARCH, 2022; 48 (7-8)

Purpose Bronchopulmonary dysplasia (BPD) is a long-term respiratory condition. More than a quarter of extremely premature newborns are harmed by BPD. ......

JIF:2.189

Insulin-like growth factor-1 reduces hyperoxia-induced lung inflammation and oxidative stress and inhibits cell apoptosis through PERK/eIF2 alpha/ATF4/CHOP signaling

期刊: EXPERIMENTAL LUNG RESEARCH, 2022; 48 (4-6)

Background: Insulin-like growth factor-1 (IGF-1), a member of the insulin family, has a high degree of homology with insulin and exhibits anti-inflamm......

JIF:2.189

SRC3 deficiency exacerbates lipopolysaccharide-induced acute respiratory distress syndrome in mice

期刊: EXPERIMENTAL LUNG RESEARCH, 2022; 48 (4-6)

Acute respiratory distress syndrome (ARDS) is a severe disease. Inflammation is the key element implicated in ARDS. Steroid receptor coactivator 3 (SR......

JIF:2.189

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