期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 145 ()
To determine whether voluntary wheel running could improve cognitive function from both the young and middle-aged APP/PS1 mice and the underlying mech......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 149 ()
The heteromeric complexes of adenosine 2A receptor (A2AR) and N-methyl-D-aspartate receptor (NMDAR) have recently been confirmed in cell experiments, ......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 144 ()
Parkinson?s disease (PD) is an age-related neurodegenerative disorder characterized by the progressive deterioration of motor function. Histopathologi......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 145 ()
Background: Chronic neuropathic pain is characterized by neuroinflammation. Previously, long noncoding RNA (lncRNA) HAGLR was reported to regulate the......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 148 ()
Objective: Chemokines regulate infiltration of immune cells to brain in inflammation. Cathepsin C (CatC), a lysosomal protease, has been found to part......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 147 ()
Ischemic stroke is a leading cause of disability and mortality worldwide due to the narrow therapeutic time window of the only two approved therapies,......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 149 ()
This study explored the role of succinate accumulation in the oxidative stress and iron accumulation in both pentylenetetrazol (PTZ)-induced epileptog......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 148 ()
Endoplasmic reticulum stress (ERS) is known to be an essential target in protecting against ischaemic brain injury. In this study, using a vascular de......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 148 ()
Central nervous system (CNS) diseases are responsible for a large proportion of morbidity and mortality worldwide. CNS diseases caused by intrinsic an......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 146 ()
Background: Parkinson?s disease is a common neurodegenerative problem. Pramipexole (PPX) plays protective role in Parkinson?s disease. Nevertheless, t......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 148 ()
Parkinson's disease (PD) is characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta and abnormal aggregates of alpha-s......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 149 ()
Inhibition of endoplasmic reticulum (ER) stress reduces blood-brain barrier (BBB) injury caused by ischemia/ reperfusion (I/R), with indistinct mechan......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 145 ()
The progressive deposition of misfolded and aggregated forms of Tau protein in the brain is a pathological hallmark of tauopathies, such as Alzheimer?......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 146 ()
In the adult brain, sonic hedgehog acts on cerebral microvascular endothelial cells to stabilize the blood-brain barrier. The expression of sonic hedg......
期刊: NEUROCHEMISTRY INTERNATIONAL, 2021; 147 ()
Glioblastoma (GBM) is a highly aggressive brain tumor. During screening work, we found a new compound named phragmunis A (PGA), which is derived from ......