期刊： STEM CELL RESEARCH, 2022; 58 ()
Hypertrophic cardiomyopathy (HCM) is characterized by impaired energy metabolism irrespective of the degree of hypertrophy. Here, we reprogrammed peri......
期刊： STEM CELL RESEARCH, 2022; 61 ()
Combined Oxidative Phosphorylation Deficiency 23 (COXPD23) caused by mutations in GTPBP3 gene is a rare mitochondrial disease. The patient-derived PBM......
期刊： STEM CELL RESEARCH, 2022; 61 ()
Alzheimer's disease (AD) is a common neurodegenerative disease characterized by cognitive decline even leading to incapacity, which prevalence estimat......
期刊： STEM CELL RESEARCH, 2022; 64 ()
ABCA4-associated retinal dystrophy is the most frequent inherited retinal dystrophy caused by biallelic variants in ABCA4 gene. We induced a new pluri......
期刊： STEM CELL RESEARCH, 2022; 59 ()
Induced pluripotent stem cells (iPSCs) are regarded as ideal cell sources of neural stem cells for the treatment of spinal cord injury (SCI). To minim......
期刊： STEM CELL RESEARCH, 2022; 60 ()
USH type 2 (USH2) is an autosomal recessive disorder that is characterized by inherited retinopathies and sensorineural hearing loss. USH type 2 (USH2......
期刊： STEM CELL RESEARCH, 2022; 59 ()
The absence of azoospermia factor c (AZFc) is a common molecular cause of sperm failure. In men with non-obstructive azoospermia or severe oligospermi......
期刊： STEM CELL RESEARCH, 2022; 61 ()
Schizophrenia is a chronic, serious and disabling mental disorder. Most patients can effectively control their condition through drug treatment, but t......
期刊： STEM CELL RESEARCH, 2022; 61 ()
Epilepsy is a common chronic neurological disorder related to genetic factors. Base on the non-integrating episomal vector technique, a human induced ......
期刊： STEM CELL RESEARCH, 2022; 62 ()
Human extended pluripotent stem cell (hEPS) is a novel type of pluripotent stem cell, which possesses bi-potency towards both embryonic and extraembry......
期刊： STEM CELL RESEARCH, 2022; 62 ()
Activated phosphoinositide 3-kinase delta syndrome (APDS) is a rare autosomal dominant primary immunodeficiency disease (PID) which was caused by the ......
期刊： STEM CELL RESEARCH, 2022; 63 ()
Long QT syndrome is one of the most common hereditary arrhythmias. Mutations in KCNH2 can cause long QT syndrome type 2 (LQT2). In this study, we gene......
期刊： STEM CELL RESEARCH, 2022; 60 ()
Mutations in the APP gene are popularly known as the second cause trigger the familial Alzheimer's disease (AD). We generated a human induced pluripot......
期刊： STEM CELL RESEARCH, 2022; 60 ()
Dominant optic atrophy (DOA) is one of the most common type of hereditary optic atrophy. Here, we describe the generation and characterization of a hu......
