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Associations between optic disc characteristics and macular choroidal microvasculature in young patients with high myopia

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2021; 49 (6)

Background This study aimed to examine changes to optic disc characteristics and macular choroidal microvasculature, and their relationships in young ......

Comparison of complications and visual outcomes between big-bubble deep anterior lamellar keratoplasty and penetrating keratoplasty for fungal keratitis

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2021; 49 (6)

Background To compare the postoperative complications and visual outcomes of big-bubble deep anterior lamellar keratoplasty (BB-DALK) and penetrating ......

MicroRNA-124 regulates lens epithelial cell apoptosis by affecting Fas alternative splicing by targeting polypyrimidine tract-binding protein in age-related cataract

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2021; 49 (6)

Background: Age-related cataract (ARC) is a primary cause of visual blindness worldwide. Lens epithelial cell (LEC) apoptosis, in which Fas plays an e......

Transepithelial corneal collagen cross-linking using iontophoresis versus the Dresden protocol in progressive keratoconus: A meta-analysis

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, ; ()

Background Standard epithelium-off collagen cross-linking using Dresden protocol (S-CXL) is the standard of care for progressive keratoconus. Despite ......

Fasting plasma glucose variability is an independent risk factor for diabetic retinopathy and diabetic macular oedema in type 2 diabetes: An 8-year prospective cohort study

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (4)

Importance Long-term stability in plasma glucose may affect the development of diabetic retinopathy (DR) and diabetic macular oedema (DMO). Background......

MiR-1246 promotes anti-apoptotic effect of mini-alpha A in oxidative stress-induced apoptosis in retinal pigment epithelial cells

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (5)

Background Geographic atrophy (GA) is a late-stage symptom of an age-related macular degeneration (AMD), characterized by the loss of retinal pigment ......

Identification of novel variants in the FZD4 gene associated with familial exudative vitreoretinopathy in Chinese families

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (3)

Background Familial exudative vitreoretinopathy (FEVR, OMIM 133780) is a severe hereditary retinal disease characterized by incomplete retinal vascula......

Impact of uveal melanoma thickness on post-plaque radiotherapy outcomes in the prophylactic anti-vascular endothelial growth factor era in 1131 patients

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (5)

Importance The impact of tumour thickness on radiation complications following plaque radiotherapy for uveal melanoma in the anti-vascular endothelial......

Mutation spectrum and genotype-phenotype correlation of inherited retinal dystrophy in Taiwan

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (4)

Background Inherited retinal dystrophy (IRD) is a group of irreversible retinal degenerative disorders with significant genotypic and phenotypic heter......

MicroRNA-184 is a key molecule responsible for the transforming growth factor-beta(2)-induced epithelial-mesenchymal transition in human lens epithelial-B3 cells

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (6)

Background TGF-beta 2-induced epithelial-mesenchymal transition (EMT) is an important mechanism for posterior capsule opacity (PCO) in lens epithelial......

Visual impairment in highly myopic eyes: The ZOC-BHVI High Myopia Cohort Study

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (6)

Importance Understanding visual impairment (VI) under different definitions and potential risk factors in high myopic is important for future myopia c......

Emerging roles of non-coding RNAs in retinal diseases: A review

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (8)

Non-coding RNAs (ncRNAs) are key players in variety of biogenesis and biological functions. Their aberrant expression has been implicated in disease p......

Association of theCAV1-CAV2locus with normal-tension glaucoma in Chinese and Japanese

期刊: CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY, 2020; 48 (5)

Background TheCAV1-CAV2locus has been associated with primary open-angle glaucoma (POAG) and intraocular pressure. However, its association with norma......

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