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miR-1287-5p upregulation inhibits the EMT and pro-inflammatory cytokines in LPS-induced human nasal epithelial cells (HNECs)

期刊: TRANSPLANT IMMUNOLOGY, 2021; 68 ()

Background: Chronic rhinosinusitis is an intractable symptom that influences daily lives of patients. miR-1287-5p was discovered to play a suppressive......

pathway to induce immune tolerance in rat heart allograft transplant

期刊: TRANSPLANT IMMUNOLOGY, 2021; 68 ()

Indoleamine 2,3-dioxygenase (IDO) can promote tryptophan metabolism to kynurenine and modulate regulatory T cells (Tregs), thereby maintains lower eff......

Sulforaphane alleviates hepatic ischemia-reperfusion injury through promoting the activation of Nrf-2/HO-1 signaling

期刊: TRANSPLANT IMMUNOLOGY, 2021; 68 ()

Background: Sulforaphane (SFN)displays both anti-oxidative stress and anti-inflammatory activity. Given that inflammation and oxidative stress play im......

Acute graft-versus-host disease after liver transplantation in a close contact with COVID-19: A case report

期刊: TRANSPLANT IMMUNOLOGY, 2021; 68 ()

Acute graft-versus-host disease (aGVHD) is a rare complication after liver transplantation that characterized by high mortality. We presented a case o......

Diphenyleneiodonium ameliorates acute liver rejection during transplantation by inhibiting neutrophil extracellular traps formation in vivo

期刊: TRANSPLANT IMMUNOLOGY, 2021; 68 ()

Neutrophil extracellular traps (NETs) play critical roles in hepatic ischemic reperfusion injury (IRI) induced immune responses to inflammation. Diphe......

A patient with end-stage renal disease who recovered from coronavirus disease 2019 then received a kidney transplant

期刊: TRANSPLANT IMMUNOLOGY, 2021; 67 ()

Since its emergence in December 2019 many end-stage renal disease (ESRD) patients have been infected with coronavirus disease 2019 (COVID-19). Herein,......

Pretransplant use of toripalimab for hepatocellular carcinoma resulting in fatal acute hepatic necrosis in the immediate postoperative period

期刊: TRANSPLANT IMMUNOLOGY, 2021; 66 ()

Immune checkpoint inhibitors are increasingly used in the treatment of various solid tumors, including hepatocellular carcinoma (HCC). For liver trans......

Regulatory T cells induce transplant immune tolerance

期刊: TRANSPLANT IMMUNOLOGY, 2021; 67 ()

Organ transplantation is the preferred treatment option for end-stage organ failure. Although immunosuppressants are effective for preventing the occu......

Vitamin D3 combined with antibody agents suppresses alloreactive memory T-cell responses to induce heart allograft long-term survival

期刊: TRANSPLANT IMMUNOLOGY, 2021; 66 ()

Background: The pre-stored memory T cells in organ transplant patient carry a high risk of allograft rejection. The current study aimed to determine w......

The use of gene-modified bone marrow mesenchymal stem cells for cochlear cell therapy

期刊: TRANSPLANT IMMUNOLOGY, 2021; 68 ()

Background: The aim of this study was to investigate the potential of using bone marrow mesenchymal stem cells (BMSCs) for treatment of inflammation a......

Increase of donor derived tumor occurrence by transfer of ex vivo expanded antigen specific regulatory T cells

期刊: TRANSPLANT IMMUNOLOGY, 2021; 66 ()

Objectives: Using regulatory T cells (Tregs) as a cellular therapy to control rejection is an attractive immunosuppressive strategy in transplantation......

De novo donor-specific HLA antibodies reduce graft survival rates and increase the risk of kidney transplant rejection: A single-center retrospective study

期刊: TRANSPLANT IMMUNOLOGY, 2021; 68 ()

Background: We investigated the impact of de novo donor-specific anti-human leukocyte antigen antibodies (dnDSAs) on long-term death-censored graft su......

Soluble CD83 inhibits acute rejection by up regulating TGF-beta and IDO secretion in rat liver transplantation

期刊: TRANSPLANT IMMUNOLOGY, 2021; 64 ()

Background: Allogeneic transplantation immune tolerance is currently a hot research issue and soluble CD83 (sCD83) is a novel immunomodulator with gre......

Implications of macrophage polarization in corneal transplantation rejection

期刊: TRANSPLANT IMMUNOLOGY, 2021; 64 ()

Corneal transplantation rejection remains an urgent problem threatening the success rate of high-risk patients. Macrophages are involved in the reject......

Gastric submucosal alleviated pro-inflammation cytokines mediated initial dysfunction of islets allografts

期刊: TRANSPLANT IMMUNOLOGY, 2021; 65 ()

Background: The liver and renal capsule are the most common site for experimental pancreatic islet transplantation, but it is not optimal. Gastric sub......

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