期刊: CANCER LETTERS, 2021; 511 ()
Immune checkpoints within the tumor microenvironment (TME) play important roles in modulating host antitumor immunity. Checkpoint-based immunotherapie......
期刊: CANCER LETTERS, 2021; 514 ()
Effective treatment regimens for triple-negative breast cancer (TNBC) are relatively scarce due to a lack of specific therapeutic targets. Epidermal g......
期刊: CANCER LETTERS, 2021; 515 ()
Resveratrol (3,4',5-trihydroxy-trans-stilbene) has been expected to ameliorate cancer and foster breakthroughs in cancer therapy. Despite thousands of......
期刊: CANCER LETTERS, 2021; 518 ()
Pancreatic ductal adenocarcinoma (PDAC) is a malignancy with poor prognosis due to early metastasis. The aberrant N6-methyladenosine (m(6)A) RNA modif......
期刊: CANCER LETTERS, 2021; 519 ()
ZEB1 is an important transcription factor that plays a critical role in TGF-beta-induced epithelial-mesenchymal transition (EMT) and tumor metastasis.......
期刊: CANCER LETTERS, 2021; 509 ()
Bladder cancer is a clinically heterogeneous disease with a poor prognosis. In the current study, anti-proliferation assay of a Euphorbiaceae diterpen......
期刊: CANCER LETTERS, 2021; 510 ()
Emerging evidence suggested that CDKN2 deletion was a poor prognosis predictor in adult B-lineage acute lymphoblastic leukemia (B-ALL). Here, we inves......
期刊: CANCER LETTERS, 2021; 516 ()
Extracellular vesicles (EVs) have gained significant attention in recent decades as major mediators of intercellular communication that are involved i......
期刊: CANCER LETTERS, 2021; 519 ()
Sorafenib and lenvatinib are approved first-line targeted therapies for advanced liver cancer, but most patients develop acquired resistance. Herein, ......
期刊: CANCER LETTERS, 2021; 519 ()
The Mas receptor has been reported to promote migration and invasion of clear cell renal cell carcinoma (ccRCC) cells via Ang-(1-7)-dependent AKT sign......
期刊: CANCER LETTERS, 2021; 519 ()
Recent studies suggest that RRP15 (Ribosomal RNA Processing 15 Homolog) might be a potential target for cancer therapy. However, the role of RRP15 in ......
期刊: CANCER LETTERS, 2021; 519 ()
Additional sex combs-like 1 (ASXL1) is frequently mutated in a variety of myeloid malignancies, resulting in expression of a C-terminal-truncated ASXL......
期刊: CANCER LETTERS, 2021; 518 ()
Cervical cancer (CC) patients with lymph node (LN) metastasis often have an extremely poor prognosis. However, the precise molecular mechanisms involv......
期刊: CANCER LETTERS, 2021; 507 ()
Urothelial carcinoma (UC) is the most common type of bladder cancer, with a 5-year survival rate of only 4.6% in metastatic UC. Despite the advances r......