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Parametric Mapping for TSPO PET Imaging with Spectral Analysis Impulsive Response Function

期刊: MOLECULAR IMAGING AND BIOLOGY, 2021; 23 (4)

Purpose The aim of this study was to investigate the use of spectral analysis (SA) for voxel-wise analysis of TSPO PET imaging studies. TSPO PET quant......

Monitoring PSMA Responses to ADT in Prostate Cancer Patient-Derived Xenograft Mouse Models Using [F-18]DCFPyL PET Imaging

期刊: MOLECULAR IMAGING AND BIOLOGY, 2021; 23 (5)

Purpose: PSMA overexpression has been associated with aggressive prostate cancer (PCa). However, PSMA PET imaging has revealed highly variable changes......

Impact of PET/MRI in the Treatment of Pancreatic Adenocarcinoma: a Retrospective Cohort Study

期刊: MOLECULAR IMAGING AND BIOLOGY, 2021; 23 (3)

Purpose: Imaging is central to the diagnosis and management of Pancreatic Ductal Adenocarcinoma (PDAC). This study evaluated if positron emission tomo......

Granzyme B PET Imaging of Combined Chemotherapy and Immune Checkpoint Inhibitor Therapy in Colon Cancer

期刊: MOLECULAR IMAGING AND BIOLOGY, 2021; 23 (5)

Purpose Chemotherapeutic adjuvants, such as oxaliplatin (OXA) and 5-fluorouracil (5-FU), that enhance the immune system, are being assessed as strateg......

Synthesis and Biological Evaluation of [F-18]FECNT-d(4) as a Novel PET Agent for Dopamine Transporter Imaging

期刊: MOLECULAR IMAGING AND BIOLOGY, 2021; 23 (5)

Purpose: The dopamine transporter (DAT) is a marker of the occurrence and development of Parkinson's disease (PD) and other diseases with nigrostriata......

Dynamic Contrast-Enhanced Ultrasound Radiomics for Hepatocellular Carcinoma Recurrence Prediction After Thermal Ablation

期刊: MOLECULAR IMAGING AND BIOLOGY, 2021; 23 (4)

Purpose To develop a radiomics model based on dynamic contrast-enhanced ultrasound (CEUS) to predict early and late recurrence in patients with a sing......

Nonconvex Laplacian Manifold Joint Method for Morphological Reconstruction of Fluorescence Molecular Tomography

期刊: MOLECULAR IMAGING AND BIOLOGY, 2021; 23 (3)

Purpose: Fluorescence molecular tomography (FMT) is a promising technique for three-dimensional (3D) visualization of biomarkers in small animals. Mor......

(2S, 4R)-4-[F-18]Fluoroglutamine for In vivo PET Imaging of Glioma Xenografts in Mice: an Evaluation of Multiple Pharmacokinetic Models

期刊: MOLECULAR IMAGING AND BIOLOGY, 2020; 22 (4)

Purpose The glutamine analogue (2S, 4R)-4-[F-18]fluoroglutamine ([F-18]FGln) was investigated to further characterize its pharmacokinetics and acquire......

Semiquantitative Parameters in PSMA-Targeted PET Imaging with [F-18]DCFPyL: Impact of Tumor Burden on Normal Organ Uptake

期刊: MOLECULAR IMAGING AND BIOLOGY, 2020; 22 (1)

Purpose In this study, we aimed to quantitatively investigate the biodistribution of [F-18]DCFPyL in patients with prostate cancer (PCa) and to determ......

Semiquantitative Parameters in PSMA-Targeted PET Imaging with [F-18]DCFPyL: Intrapatient and Interpatient Variability of Normal Organ Uptake

期刊: MOLECULAR IMAGING AND BIOLOGY, 2020; 22 (1)

Purpose Prostate-specific membrane antigen (PSMA)-targeted positron emission tomography (PET) imaging has impacted the management of patients with pro......

Radiofluorinated GPC3-Binding Peptides for PET Imaging of Hepatocellular Carcinoma

期刊: MOLECULAR IMAGING AND BIOLOGY, 2020; 22 (1)

Purpose Hepatocellular carcinoma (HCC) remains one of the most challenging diseases worldwide. Glypican-3 (GPC-3) is a cell surface proteoglycan that ......

Evaluation of Glycolytic Response to Multiple Classes of Anti-glioblastoma Drugs by Noninvasive Measurement of Pyruvate Kinase M2 Using [F-18]DASA-23

期刊: MOLECULAR IMAGING AND BIOLOGY, 2020; 22 (1)

Purpose Pyruvate kinase M2 (PKM2) catalyzes the final step in glycolysis, the key process of tumor metabolism. PKM2 is found in high levels in gliobla......

Research Progress of [Ga-68]Citrate PET's Utility in Infection and Inflammation Imaging: a Review

期刊: MOLECULAR IMAGING AND BIOLOGY, 2020; 22 (1)

Imaging diagnosis of infection and inflammation has been challenging for many years. Infection imaging agents commonly used in nuclear medicine, such ......

Assessment of Metastatic and Reactive Sentinel Lymph Nodes with B7-H3-Targeted Ultrasound Molecular Imaging: A Longitudinal Study in Mouse Models

期刊: MOLECULAR IMAGING AND BIOLOGY, 2020; 22 (4)

Purpose To explore the potential of B7-H3-targeted ultrasound molecular imaging (USMI) for longitudinal assessment and differentiation of metastatic a......

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