期刊: IMMUNOLOGICAL REVIEWS, 2021; 303 (1)
Humoral immunity provides protection from pathogenic infection and is mediated by antibodies following the differentiation of naive B cells (nBs) to a......
期刊: IMMUNOLOGICAL REVIEWS, 2021; 302 (1)
The incidence of inflammatory bowel diseases (IBD) worldwide has resulted in a global public health challenge. Intestinal fibrosis leading to strictur......
期刊: IMMUNOLOGICAL REVIEWS, 2020; 296 (1)
B cells have been known for their ability to present antigens to T cells for almost 40 years. However, the precise roles of B cell antigen presentatio......
期刊: IMMUNOLOGICAL REVIEWS, 2020; 295 (1)
The metabolism of healthy murine and more recently human immune cells has been investigated with an increasing amount of details. These studies have r......
期刊: IMMUNOLOGICAL REVIEWS, 2020; 297 (1)
Innate sensors recognize pathogen-associated molecular patterns (PAMPs) or damage-associated molecular patterns (DAMPs) to initiate innate immune resp......
期刊: IMMUNOLOGICAL REVIEWS, 2020; 298 (1)
Unique V gamma 2V delta 2 (V gamma 9V delta 2) T cells existing only in human and non-human primates, account for the majority of circulating gamma de......
期刊: IMMUNOLOGICAL REVIEWS, 2019; 288 (1)
Follicular T-helper (T-FH) cells play a crucial role in three aspects of the germinal center (GC) response. They promote GC formation, arbitrate compe......
期刊: IMMUNOLOGICAL REVIEWS, 2019; 291 (1)
To efficiently initiate activation responses against rare ligands in the microenvironment, lymphocytes employ sophisticated mechanisms involving signa......
期刊: IMMUNOLOGICAL REVIEWS, 2019; 292 (1)
One of the biggest barriers to achieving allograft tolerance is the presence of immunological memory within the recipient, which confers a faster, mor......
期刊: IMMUNOLOGICAL REVIEWS, 2019; 292 (1)
Allograft tolerance is the ultimate goal of organ transplantation. Current strategies for tolerance induction mainly focus on inhibiting alloreactive ......
期刊: IMMUNOLOGICAL REVIEWS, 2017; 276 (1)
Immune responses must be fine-tuned to allow effective clearance of invading pathogens, while maintain tolerance to self-antigens. T cells are the maj......
期刊: IMMUNOLOGICAL REVIEWS, 2017; 278 (1)
IL-25, also known as IL-17E, is a member of the IL-17 cytokine family mostly produced by epithelial cells and innate immune cells. After binding to th......
期刊: IMMUNOLOGICAL REVIEWS, 2017; 280 (1)
Cancer therapies can temporarily reduce tumor burdens by inducing malignant cell death. However, cancer cure is still far from realization because tum......
期刊: IMMUNOLOGICAL REVIEWS, 2022; 308 (1)
Maternal tolerance to semi- or fully allograft conceptus is a prerequisite for the maintenance of pregnancy. Once this homeostasis is disrupted, it ma......
期刊: IMMUNOLOGICAL REVIEWS, 2022; 308 (1)
Successful pregnancy is a unique situation requires the maternal immune system to recognize and tolerate a semi-identical fetus and allow normal invas......