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Novel serum autoantibodies against ss-actin (ACTB) in amyotrophic lateral sclerosis

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2021; 22 (5-6)

To identify novel biomarkers using the serological analysis of recombinant cDNA expression libraries (SEREX) method and to evaluate their clinical sig......

Genetics of frontotemporal dementia in China

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, ; ()

Backgbround: Frontotemporal dementia (FTD) is the second most common presenile dementia, characterized by prominent behavioral, language, and cognitiv......

A de novo c.1509dupA:p.R503fs mutation ofFUS: report of a girl with sporadic juvenile amyotrophic lateral sclerosis

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2020; 21 (7-8)

Juvenile amyotrophic lateral sclerosis (JALS) is a rare and severe form of ALS. The development of sequencing methods has resulted in increased report......

Serum creatinine levels in patients with amyotrophic lateral sclerosis: a systematic review and meta-analysis

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2020; 21 (7-8)

Background:Serum creatinine (Cr) is a biosynthetic product of creatine phosphate metabolism in muscles and is closely related to total muscle mass, bu......

A prospective study on split-hand index as a biomarker for the diagnosis of amyotrophic lateral sclerosis

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2020; 21 (7-8)

Objective:To determine the practical diagnostic utility of split-hand index (SI) values calculated from F-wave persistence (SIFP) and the F/M amplitud......

NEK1 and GRN mutations coexist in a sporadic Chinese Hui descent ALS patient

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2020; 21 (7-8)

We describe a sporadic amyotrophic lateral sclerosis (ALS) patient who presented rapid progress of muscle weakness and died of respiratory failure one......

Clinical disease stage related changes of serological factors in amyotrophic lateral sclerosis

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2019; 20 (1-2)

Objective: Little is known whether disease clinical stage would influence the serological values in Amyotrophic lateral sclerosis (ALS). We aimed to e......

JIF:2.88

Cognitive and behavioral impairments in German and Chinese ALS populations - a post-hoc comparison of national study data

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2019; 20 (1-2)

This study aimed to clarify whether differences between German and Chinese studies using the standardized Edinburgh Cognitive and Behavioural ALS Scre......

JIF:2.88

Elevated serum ferritin level as a predictor of reduced survival in patients with sporadic amyotrophic lateral sclerosis in China: a retrospective study

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2019; 20 (3-4)

Objective: The objective of this study was to compare iron metabolic variables in the serum and cerebrospinal fluid (CSF) of patients with sporadic am......

JIF:2.88

Split-hand index in amyotrophic lateral sclerosis: an F-wave study

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2019; 20 (7-8)

Objective: Split-hand sign is a useful clinical and electrophysiological feature in the diagnosis of amyotrophic lateral sclerosis (ALS). We proposed ......

JIF:2.88

Twelve-month duration as an appropriate criterion for flail arm syndrome

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 0; ()

Objectives: To analyze the clinical features of flail arm syndrome (FAS) in a large Chinese clinic-based cohort, and to discuss whether it is proper t......

The protective role of pre-morbid type 2 diabetes in patients with amyotrophic lateral sclerosis: a center-based survey in China

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 0; ()

Objective: To assess the role of premorbid type 2 diabetes in patients with amyotrophic lateral sclerosis (ALS) in China. Methods: We compared data fr......

Identification and functional analysis of novel mutations in the SOD1 gene in Chinese patients with amyotrophic lateral sclerosis

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2019; 20 (3-4)

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease characterized by selective involvement of motor neurons in the central ......

JIF:2.88

Lack of association between the P413L variant of chromogranin B and ALS risk or age at onset: a meta-analysis

期刊: AMYOTROPHIC LATERAL SCLEROSIS AND FRONTOTEMPORAL DEGENERATION, 2018; 19 (1-2)

Background: Amyotrophic lateral sclerosis (ALS), the most common motor neuron disease, is thought to result from interaction of genetic and environmen......

JIF:2.88

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