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Environmental level of the antidepressant venlafaxine induces behavioral disorders through cortisol in zebrafish larvae (Danio rerio)

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2021; 83 ()

Psychoactive drugs discharged into the environment have different effects on the behavior of vertebrates. The objective of this study was to evaluate ......

Organophosphorus-based chemical additives induced behavioral changes in zebrafish (Danio rerio): Swimming activity is a sensitive stress indicator

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2021; 83 ()

Organophosphorus flame retardants (OPFRs) have been extensively used as chemical additives in polymer based consumer products. Among them, Isopropylph......

Effects of in utero exposure to lanthanum on neurological behavior in rat offspring

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2020; 77 ()

The increasing use of rare-earth elements in various fields has raised concern from public heath perspective regarding their accumulation in human bod......

Inhibition of the electron transport chain in propofol induced neurotoxicity in zebrafish embryos

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2020; 78 ()

Fetal and neonatal exposure to propofol can lead to neuronal death and long-term neurobehavioral deficiencies in both rodents and nonhuman primates. Z......

Behavioral and physiological effects of acute and chronic kava exposure in adult zebrafish

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2020; 79 ()

Kava kava (Piper methysticum) is a medicinal plant containing kavalactones that exert potent sedative, analgesic and anti-stress action. However, thei......

Sub-lethal toxicity assessment of the phenylurea herbicide linuron in developing zebrafish (Danio rerio) embryo/larvae

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2020; 81 ()

Due to run-off and rain events, agrochemicals can enter water catchments, exerting endocrine disruption effects and toxicity to aquatic organisms. Lin......

Organophosphorus flame retardant induced hepatotoxicity and brain AChE inhibition on zebrafish (Danio rerio)

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2020; 82 ()

Organophosphorus flame retardants (OPFRs) are high production volume (HPV) chemicals. Recent reports reveal that OPFRs are ubiquitous in the environme......

Venlafaxine plus melatonin ameliorate reserpine-induced depression-like behavior in zebrafish

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2019; 76 ()

Venlafaxine (VEN) is one of the first clinical drugs for the treatment of depression. Long-term use may cause a potentially life-threatening serotonin......

JIF:2.9

Analgesic and toxic effects of venenum bufonis and its constituent compound cinobufagin: A comparative study

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2019; 73 ()

Objective: In this study, we aimed to compare the analgesic and toxic effects of Venenum Bufonis (VB) with those of cinobufagin (CBG), a monomer isola......

JIF:2.9

The citrus flavonoids hesperidin and naringin alleviate alcohol-induced behavioural alterations and developmental defects in zebrafish larvae

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2019; 73 ()

This study aimed to investigate the protective effects of two citrus flavonoids, hesperidin and naringin, on alcohol-induced thigmotaxis behavioural a......

JIF:2.9

Developmental neurotoxicity in the context of multiple sevoflurane exposures: Potential role of histone deacetylase 6

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2019; 74 ()

Animal studies have demonstrated that multiple exposures to sevoflurane during the postnatal period lead to impaired synaptogenesis and cognitive defi......

JIF:2.9

ROS-mediated JNK pathway critically contributes to PFOS-triggered apoptosis in SH-SY5Y cells

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2019; 75 ()

Recent studies have indicated that perfluorooctane sulfonate (PFOS) and its derivatives can lead to neurotoxicity. In the present study, we showed tha......

JIF:2.9

When fish take a bath: Psychopharmacological characterization of the effects of a synthetic cathinone bath salt 'flakka' on adult zebrafish

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2019; 73 ()

Alpha-pyrrolidinopentiophenone (alpha-PVP) is a synthetic cathinone which exerts robust mental and physiological effects clinically, as well as causes......

JIF:2.9

Anesthetics disrupt growth cone guidance cue sensing through actions on the GABA(A) alpha 2 receptor mediated by the immature chloride gradient

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2019; 74 ()

Background: General anesthetics (GAs) may exert harmful effects on the developing brain by disrupting neuronal circuit formation. Anesthetics that act......

JIF:2.9

Emulsified isoflurane induces release of cytochrome C in human neuroblastoma SHSY-5Y cells via JNK (c-Jun N-terminal kinases) signaling pathway

期刊: NEUROTOXICOLOGY AND TERATOLOGY, 2018; 65 ()

A large number of studies have demonstrated that inhalation anesthetic isoflurane induced neural cell death by apoptosis in various cell and animal mo......

JIF:2.9

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