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Rapid assembly of alpha-ketoamides through a decarboxylative strategy of isocyanates with alpha-oxocarboxylic acids under mild conditions

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (21)

A simple and practical method for alpha-ketoamide synthesis via a decarboxylative strategy of isocyanates with alpha-oxocarboxylic acids is described.......

Highly selective C3-H iodination of pyrrolo[1,2-a]quinoxalines

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (23)

We report a C3-H direct iodination of pyrrolo[1,2-a]quinoxalines with TBAI or I-2; a series of novel 3-iodopyrrolo[1,2-a]quinoxaline derivatives were ......

Lewis acid-promoted formation of benzoselenazole derivatives using SeO2 as a selenium source

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (30)

A new one-pot method of using both ortho-inactivated anilines and acetophenones (or methylquinolines) which possess an active H in the alpha-position ......

A metal-free radical cascade reaction of phosphine oxides with 2-aryloxy phenylacetylenes to synthesize diphosphonyl xanthene derivatives

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (30)

A radical cascade reaction of 2-aryloxy phenylacetylenes with phosphine oxides promoted by K2S2O8 was developed, which provided diphosphonyl xanthenes......

A phosphine-catalysed one-pot domino sequence to access cyclopentene-fused coumarins

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (32)

A novel phosphine-catalysed, one-pot domino approach for the annulation of 2-formylphenyl alkynoates with activated methylene compounds to construct v......

Palladium-catalyzed cascade 5-exo-trig radical cyclization/aromatic C-H alkylation with unactivated alkyl iodides

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (12)

A novel and convenient palladium-catalyzed cascade 5-exo-trig radical cyclization/aromatic C-H alkylation with unactivated alkyl iodides has been desc......

Metal-free access to 3-allyl-2-alkoxychromanones via phosphine-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (12)

A metal-free access to 3-allyl-2-alkoxychromanones by PPh3-catalyzed alkoxy allylation of chromones with MBH carbonates and alcohols is described. Thi......

A copper iodide-catalyzed coupling reaction of benzofuran-3(2H)-ones with amines: an approach to alpha-ketoamides

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (24)

A CuI-catalyzed coupling reaction of benzofuran-3(2H)-ones with amines has been well established for the direct synthesis of alpha-ketoamides. This pr......

Indium-mediated annulation of 2-azidoaryl aldehydes with propargyl bromides to [1,2,3]triazolo[1,5-a]quinolines

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (28)

An efficient indium-mediated cascade annulation reaction of 2-azidoaryl aldehydes with propargyl bromides is reported. The aromatic 5/6/6-fused hetero......

Microfluidic synthesis of pyrrolidin-2-ones via photoinduced organocatalyzed cyclization of styrene, alpha-bromoalkyl esters and primary amines

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (29)

A green and efficient reaction route for the synthesis of pyrrolidin-2-ones via photoinduced organocatalyzed three-component cyclization of styrene, t......

Psidguajones A and B, a pair of complex meroterpenoid epimers from the leaves of Psidium guajava

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (25)

Psidguajones A and B, a pair of dimeric sesquiterpene-based meroterpenoid epimers, have been isolated from the leaves of Psidium guajava for the first......

Advances of alpha-activated cyclic isothiocyanate for the enantioselective construction of spirocycles

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (21)

The efficient and enantioselective synthesis of pharmaceutically important spirocycles has attracted the focus of organic and medicinal chemists. In t......

A three-component iodine-catalyzed oxidative coupling reaction: a heterodifunctionalization of 3-methylindoles

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (26)

A metal-free method for the synthesis of heterodifunctional indole derivatives is developed through TBHP/KI-mediated oxidative coupling. The reaction ......

n-Butyllithium as a highly efficient precatalyst for cyanosilylation of aldehydes and ketones

期刊: ORGANIC & BIOMOLECULAR CHEMISTRY, 2021; 19 (34)

A highly efficient cyanosilylation protocol mediated by the easily available n-BuLi with a wide range of aldehydes and ketones was developed. This pro......

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