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Neurological aspects of SARS-CoV-2 infection: lipoproteins and exosomes as Trojan horses

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2022; 33 (8)

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) primarily targets lipid-producing cells for viral tropism. In this review, we connect sys......

JIF:7.713

MANF: an emerging therapeutic target for metabolic diseases

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2022; 33 (4)

Mesencephalic astrocyte-derived neurotrophic factor (MANF) is an endoplasmic reticulum-resident protein and a secretory factor and has beneficial effe......

JIF:7.713

Metabolic disorders on cognitive dysfunction after traumatic brain injury

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2022; 33 (7)

Cognitive dysfunction is a common adverse consequence of traumatic brain injury (TBI). After brain injury, the brain and other organs trigger a series......

JIF:7.713

Metabolic changes favor the activity and heterogeneity of reactive astrocytes

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2022; 33 (6)

Reactive astrocytes undergo morphological, molecular, metabolic, and functional remodeling in response to central nervous system (CNS) damage. However......

JIF:7.713

Irisin, a fascinating field in our times

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2022; 33 (9)

Irisin is a muscle-secreted hormone that is generated by cleavage of membrane protein FNDC-5 (fibronectin type III domain-containing protein 5). Irisi......

JIF:7.713

Decoding genome recombination and sex reversal

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2022; 33 (3)

Over the past 440 years since the discovery of the medicinal value of swamp eels, much progress has been made in the study of their biology. The fish ......

JIF:7.713

Old Paradoxes and New Opportunities for Appetite Control in Obesity

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2021; 32 (5)

Human obesity is accompanied by alterations in the blood concentrations of multiple circulating appetite regulators. Paradoxically, most of the appeti......

From Pharmacology to Physiology: Endocrine Functions of mu-Opioid Receptor Networks

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2021; 32 (5)

The steady rise in opioid users and abusers has uncovered multiple detrimental health consequences of perturbed opioid receptor signaling, thereby cre......

Taurine Makes Our Microbiota Stronger

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2021; 32 (5)

Our gut microbiota is known as an efficient barrier for infection; however, the physiological processes involved are poorly understood. Stacy et al. r......

Ferritinophagy and ferroptosis in the management of metabolic diseases

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2021; 32 (7)

Ferroptosis is a form of regulated cell death modality associated with disturbed iron-homeostasis and unrestricted lipid peroxidation. Ample evidence ......

Roles of TGF-beta Superfamily Proteins in Extravillous Trophoblast Invasion

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2021; 32 (3)

Following embryo implantation, extravillous trophoblasts (EVTs) invade the maternal decidua to a certain extent during early pregnancy, which is criti......

Butyrate in Energy Metabolism: There Is Still More to Learn

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2021; 32 (3)

Butyrate, a main product of gut microbial fermentation, has been recognized as an important mediator of gut microbiota regulation in whole body energy......

Immunoregulatory Functions of Nuclear Receptors: Mechanisms and Therapeutic Implications

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2020; 31 (2)

Members of the nuclear receptor superfamily serve as master regulators in signaling by either positively or negatively regulating gene expression. Acc......

Impacts of Caffeine during Pregnancy

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2020; 31 (3)

Epidemiological studies have revealed that caffeine consumption during pregnancy is associated with adverse gestational outcomes, yet the underlying m......

Familial Hypercholesterolemia and Atherosclerosis: Animal Models and Therapeutic Advances

期刊: TRENDS IN ENDOCRINOLOGY AND METABOLISM, 2020; 31 (5)

Familial hypercholesterolemia (FH), mainly arising from loss-of-function mutation of the low-density lipoprotein receptor (LDLR), is a life-threatenin......

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