期刊： HUMAN GENE THERAPY, 2022; 33 (11-12)
To develop genetically engineered bone marrow mesenchymal stem cells (BMSCs) that carries a radiotherapy gene to target triple-negative breast cancer ......
期刊： HUMAN GENE THERAPY, 2022; 33 (7-8)
Hemophilia A (HA) is a monogenic disease characterized by plasma clotting factor 8 (F8) deficiency due to F8 mutation. We have been attempting to cure......
期刊： HUMAN GENE THERAPY, 2022; 33 (13-14)
The safety, biodistribution, and pharmacokinetics of any new therapeutic tumor DNA vaccine must be evaluated in preclinical studies. We previously dev......
期刊： HUMAN GENE THERAPY, 2022; 33 (23-24)
The treatment of malignant tumors has always been one of the challenges that have plagued researchers and clinicians. The ideal status in cancer treat......
期刊： HUMAN GENE THERAPY, 2022; 33 (11-12)
Hair follicle stem cells (HFSCs) are responsible for hair growth and hair follicle regeneration. MicroRNAs have been demonstrated to be involved in th......
期刊： HUMAN GENE THERAPY, 2022; 33 (5-6)
The phenomenon of no-reflow seriously limits the therapeutic value of coronary recanalization and leads to poor prognosis. Recent studies have demonst......
期刊： HUMAN GENE THERAPY, 2022; 33 (23-24)
Gene therapy's entrance into clinical settings has made it an ever more attractive field of study for various diseases. However, relatively little pro......
期刊： HUMAN GENE THERAPY, 2022; 33 (5-6)
Neutralizing antibodies (NAbs) strongly limit adeno-associated virus (AAV) vector transduction and repeated administration. Previous studies have show......
期刊： HUMAN GENE THERAPY, 2022; 33 (19-20)
Sepsis is a common life-threatening pathology. This study investigated the role of transcription factor sex-determining region Y (SRY)-box 9 (SOX9) in......
期刊： HUMAN GENE THERAPY, 2022; 33 (13-14)
Adeno-associated virus (AAV)-based gene therapy has been demonstrated to be extremely effective for treating genetic hearing loss over the past severa......
期刊： HUMAN GENE THERAPY, 2022; 33 (5-6)
Solid tumors are characterized by abundant extracellular matrix originating from cancer-associated fibroblasts (CAFs). High collagen content can trigg......
期刊： HUMAN GENE THERAPY, 2022; 33 (13-14)
Adeno-associated virus (AAV) are potent vectors to achieve treatment against hearing loss resulting from genetic defects. However, the effects of deli......
期刊： HUMAN GENE THERAPY, 2022; 33 (21-22)
This article systematically discusses Chinese current legal status and rules for human embryo gene editing in both administrative law and criminal law......
期刊： HUMAN GENE THERAPY, 2022; 33 (11-12)
Obesity has become a serious global public health problem, and cardiomyopathy caused by obesity has recently gained attention. As an important protein......
期刊： HUMAN GENE THERAPY, 2022; 33 (7-8)
The clustered regularly interspaced short palindromic repeats (CRISPR) system is inarguably the most valuable gene editing tool ever discovered. Curre......
