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Modelling dynamics of coronavirus disease 2019 spread for pandemic forecasting based on Simulink

期刊: PHYSICAL BIOLOGY, 2021; 18 (4)

In this paper, we demonstrate the application of MATLAB to develop a pandemic prediction system based on Simulink. The susceptible-exposed-asymptomati......

Deriving time-varying cellular motility parameters via wavelet analysis

期刊: PHYSICAL BIOLOGY, 2021; 18 (4)

Cell migration, which is regulated by intracellular signaling pathways (ICSP) and extracellular matrix (ECM), plays an indispensable role in many phys......

Emerging machine learning approaches to phenotyping cellular motility and morphodynamics

期刊: PHYSICAL BIOLOGY, 2021; 18 (4)

Cells respond heterogeneously to molecular and environmental perturbations. Phenotypic heterogeneity, wherein multiple phenotypes coexist in the same ......

Roadmap on emerging concepts in the physical biology of bacterial biofilms: from surface sensing to community formation

期刊: PHYSICAL BIOLOGY, 2021; 18 (5)

Bacterial biofilms are communities of bacteria that exist as aggregates that can adhere to surfaces or be free-standing. This complex, social mode of ......

Multi-scale simulation of early kidney branching morphogenesis

期刊: PHYSICAL BIOLOGY, 2021; 18 (2)

An important feature of the branch morphogenesis during kidney development is the termination of the tips on the outer surface of a kidney. This featu......

From reversible to irreversible bistable switches via bifurcations in a gene regulatory network

期刊: PHYSICAL BIOLOGY, 2020; 17 (4)

The interplay of small, noncoding microRNAs (miRNAs), mRNAs and proteins plays crucial roles in almost all cellular processes. MiR-124, widely known a......

O-GlcNAcylation inhibits the oligomerization of alpha-synuclein by declining intermolecular hydrogen bonds through a steric effect

期刊: PHYSICAL BIOLOGY, 2020; 18 (1)

Toxic abnormal aggregation of alpha-synuclein (alpha-Syn) is a feature of Parkinson's disease. Several biochemical and biophysical studies have demons......

Why and how the nematode's early embryogenesis can be precise and robust: a mechanical perspective

期刊: PHYSICAL BIOLOGY, 2020; 17 (2)

The early embryogenesis in the nematode Caenorhabditis elegans is well-known for its stereotypic precision of cell arrangements and their lineage rela......

Bi-functional biochemical networks

期刊: PHYSICAL BIOLOGY, 2019; 16 (1)

Understanding the relationship between the topology of a network and its function remains an important question in biological physics. However, this i......

JIF:1.82

DCA for genome-wide epistasis analysis: the statistical genetics perspective

期刊: PHYSICAL BIOLOGY, 2019; 16 (2)

Direct coupling analysis (DCA) is a now widely used method to leverage statistical information from many similar biological systems to draw meaningful......

JIF:1.82

Novel inverse finite-element formulation for reconstruction of relative local stiffness in heterogeneous extra-cellular matrix and traction forces on active cells

期刊: PHYSICAL BIOLOGY, 2019; 16 (3)

Accurately resolving the traction forces on active cells in 3D extra-cellular matrix (ECM) is crucial to understanding stress homeostasis in cellulari......

JIF:1.82

Epithelial-to-mesenchymal transition: lessons from development, insights into cancer and the potential of EMT-subtype based therapeutic intervention

期刊: PHYSICAL BIOLOGY, 2019; 16 (4)

Epithelial-to-mesenchymal transition (EMT) is a fundamental developmental process wherein polarized epithelial cells lose their junctional architectur......

JIF:1.82

Landscape perspectives of tumor, EMT, and development

期刊: PHYSICAL BIOLOGY, 2019; 16 (5)

A tumor is rarely fatal until becoming metastatic. Recent discoveries suggest that epithelial mesenchymal transition(EMT) is an important process whic......

JIF:1.82

Glycolytic reprogramming in cancer cells: PKM2 dimer predominance induced by pulsatile PFK-1 activity

期刊: PHYSICAL BIOLOGY, 2019; 16 (6)

The glycolytic enzyme pyruvate kinase M2 (PKM2) exists in both catalytically inactive dimeric and active tetrameric forms. In cancer cells, PKM2 dimer......

JIF:1.82

Spatiotemporal feedforward between PKM2 tetramers and mTORC1 prompts mTORC1 activation

期刊: PHYSICAL BIOLOGY, 2022; 19 (4)

Most mammalian cells couple glucose availability to anabolic processes via the mTORC1 pathway. However, the mechanism by which fluctuations in glucose......

JIF:2.68

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