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Presynaptic HCN channels constrain GABAergic synaptic transmission in pyramidal cells of the medial prefrontal cortex

期刊: BIOLOGY OPEN, 2022; 11 (3)

Hyperpolarization-activated cyclic nucleotide-gated (HCN) channels are widely expressed in neurons in the central nervous system. It has been document......

JIF:2.088

DNMT1 is a negative regulator of osteogenesis

期刊: BIOLOGY OPEN, 2022; 11 (3)

The role and underlying mechanisms of DNA methylation in osteogenesis/chondrogenesis remain poorly understood. We here reveal DNA methyltransferase 1 ......

JIF:2.088

Genome wide association study for the identification of genes associated with tail fat deposition in Chinese sheep breeds

期刊: BIOLOGY OPEN, 2021; 10 (5)

Chinese indigenous sheep can be classified into three types based on tail morphology: fat-tailed, fat-rumped, and thin-tailed sheep, of which the typi......

miR-8b is involved in brain and eye regeneration of Dugesia japonica in head regeneration

期刊: BIOLOGY OPEN, 2021; 10 (6)

MicroRNAs (miRNAs) are a class of evolutionarily conserved small non-coding RNAs that regulate gene expression at the translation level in cell growth......

High glucose induces Nox4 expression and podocyte apoptosis through the Smad3/ezrin/PKA pathway

期刊: BIOLOGY OPEN, 2021; 10 (5)

Podocytes are the major target in proteinuric kidney diseases such as diabetic nephropathy. The underlying molecular mechanisms by which high glucose ......

LIM Homeobox 9 knockdown by morpholino does not affect zebrafish retinal development

期刊: BIOLOGY OPEN, 2021; 10 (3)

LIM homeobox 9 (Lhx9) is a member of the LIM homeodomain transcription factor family, which expresses and functions in various vertebrate tissues, suc......

Morphological mechanism allowing a parasitic leech, Ozobranchus jantseanus (Rhynchobdellida: Ozobranchidae), to survive in ultra-low temperatures

期刊: BIOLOGY OPEN, 2021; 10 (7)

Ozobranchus jantseanus is the largest metazoan known to survive in liquid nitrogen without pretreatment to date; however, the mechanism underlying thi......

The thermal dependence and molecular basis of physiological color change in Takydromus septentrionalis (Lacertidae)

期刊: BIOLOGY OPEN, 2021; 10 (3)

One of the main functions of physiological color change is thermoregulation. This change occurs much more rapidly than morphological color change, but......

First person - Michel A. K. Dongmo

期刊: BIOLOGY OPEN, 2021; 10 (4)

First Person is a series of interviews with the first authors of a selection of papers published in Biology Open, helping early-career researchers pro......

Establishment of Etv5 gene knockout mice as a recipient model for spermatogonial stem cell transplantation

期刊: BIOLOGY OPEN, 2021; 10 (1)

Spermatogonial stem cell (SSC) transplantation is an alternative reproductive method to achieve conservation and production of elite animals in livest......

Variation in alarm calls during different breeding stages of the common kestrel (Falco tinnunculus)

期刊: BIOLOGY OPEN, 2021; 10 (1)

Acoustic signals play a key role in animal communication. Animals usually use alarm signals to warn mates or offspring of the presence of threats or t......

Single-cell sequencing reveals the potential oncogenic expression atlas of human iPSC-derived cardiomyocytes

期刊: BIOLOGY OPEN, 2021; 10 (2)

Human induced pluripotent stem cells (iPSCs) are important source for regenerative medicine. However, the links between pluripotency and oncogenic tra......

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