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Cost-effectiveness Analysis of Trastuzumab Emtansine as Second-line Therapy for HER2-Positive Breast Cancer in China

期刊: CLINICAL DRUG INVESTIGATION, 2021; 41 (6)

Background and Objective Trastuzumab emtansine (T-DM1) is the standard second-line option for the treatment of patients with human epidermal growth fa......

Sodium-Glucose Cotransporter Inhibitors for the Treatment of Type 1 Diabetes Mellitus

期刊: CLINICAL DRUG INVESTIGATION, 2020; 40 (11)

Sodium-glucose cotransporter inhibitors are a new class of oral antihyperglycemic drugs that have been approved for the treatment of patients with typ......

The Prediction Model of Warfarin Individual Maintenance Dose for Patients Undergoing Heart Valve Replacement, Based on the Back Propagation Neural Network

期刊: CLINICAL DRUG INVESTIGATION, 2020; 40 (1)

Background and ObjectiveBecause of the narrow therapeutic window and huge inter-individual variation, the individual precision on anticoagulant therap......

Cost-effectiveness Analysis of CYP2D6*10 Pharmacogenetic Testing to Guide the Adjuvant Endocrine Therapy for Postmenopausal Women with Estrogen Receptor Positive Early Breast Cancer in China

期刊: CLINICAL DRUG INVESTIGATION, 2020; 40 (1)

BackgroundA CYP2D6 gene polymorphism is related to the effect of tamoxifen treatment in patient with estrogen-receptor positive (ER) positive breast c......

Cost Effectiveness of Ceritinib and Alectinib Versus Crizotinib in First-Line Anaplastic Lymphoma Kinase-Positive Advanced Non-small-cell Lung Cancer

期刊: CLINICAL DRUG INVESTIGATION, 2020; 40 (2)

BackgroundCrizotinib, ceritinib, and alectinib improved survival in patients with anaplastic lymphoma kinase (ALK) arrangement non-small-cell lung can......

A Caprini Risk Score-Based Cost-Effectiveness Analysis of Enoxaparin for the Thromboprophylaxis of Patients After Nonorthopedic Surgery in a Chinese Healthcare Setting

期刊: CLINICAL DRUG INVESTIGATION, 2020; 40 (2)

BackgroundVenous thromboembolism (VTE), which includes deep vein thrombosis (DVT) and pulmonary embolism (PE), is an important cause of post-surgery m......

Comparative Study of Traditional Ablative CO2 Laser-Assisted Topical Antifungal with only Topical Antifungal for Treating Onychomycosis: A Multicenter Study

期刊: CLINICAL DRUG INVESTIGATION, 2020; 40 (6)

Background The predominance of onychomycosis has been increasing recently. New medications and treatment modalities are being researched for better sa......

Rational Use of Tocilizumab in the Treatment of Novel Coronavirus Pneumonia

期刊: CLINICAL DRUG INVESTIGATION, 2020; 40 (6)

Since December 2019, a novel coronavirus pneumonia (COVID-19) has broken out in Wuhan, China and spread rapidly. Recent studies have found that & ......

Pharmacokinetics and Bioequivalence Evaluation of a New Oxycodone Tamper-Resistant Tablet Administered with an Opioid Antagonist in Patients with Chronic Pain

期刊: CLINICAL DRUG INVESTIGATION, 0; ()

Background and Objectives Oxycodone tamper resistant (OTR) is a new extended-release abuse-deterrent formulation providing improvements in the tamper ......

Nivolumab Versus Docetaxel for Previously Treated Advanced Non-Small Cell Lung Cancer in China: A Cost-Effectiveness Analysis

期刊: CLINICAL DRUG INVESTIGATION, 0; ()

Background and Objective The economic assessment of immuno-oncology agents in Chinese patients is limited despite a need for new therapies. Nivolumab ......

Pharmacokinetics, Safety and Tolerability of Tylerdipine Hydrochloride, a Novel Dihydropyridine Dual L/T-type Calcium Channel Blocker, after Single and Multiple Oral Doses in Healthy Chinese Subjects

期刊: CLINICAL DRUG INVESTIGATION, 2019; 39 (1)

Background and ObjectiveTylerdipine hydrochloride (KBP-5660) is a novel L/T-type dual calcium channel blocker developed for thetreatment of hypertensi......

JIF:2.16

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