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Multi-omics analyses of the transition to the Crabtree effect in S. cerevisiae reveals a key role for the citric acid shuttle

期刊: FEMS YEAST RESEARCH, 2022; 22 (1)

The article investigates the Crabtree effect under dynamic process which have never been reported, and find the citric acid shuttles to support higher......

JIF:2.637

Differential analysis of ergosterol function in response to high salt and sugar stress in Zygosaccharomyces rouxii

期刊: FEMS YEAST RESEARCH, 2022; 22 (1)

Ergosterol synthesis has functional differences in Zygosaccharomyces rouxii response to high salt and high sugar stress. Zygosaccharomyces rouxii is a......

JIF:2.637

A review of yeast: High cell-density culture, molecular mechanisms of stress response and tolerance during fermentation

期刊: FEMS YEAST RESEARCH, 2022; 22 (1)

Yeast is widely used in the fermentation industry, and the major challenges in fermentation production system are high capital cost and low reaction r......

JIF:2.637

Genome-wide transcriptional regulation in Saccharomyces cerevisiae in response to carbon dioxide

期刊: FEMS YEAST RESEARCH, 2022; 22 (1)

Sugar metabolism by Saccharomyces cerevisiae produces ample amounts of CO2 under both aerobic and anaerobic conditions. High solubility of CO2 in ferm......

JIF:2.637

Utilization of ethanol for itaconic acid biosynthesis by engineered Saccharomyces cerevisiae

期刊: FEMS YEAST RESEARCH, 2021; 21 (6)

In Saccharomyces cerevisiae, ethanol can serve as both a carbon source and NADH donor for the production of acetyl-CoA derivatives. Here we investigat......

Epigenetic regulation of virulence and the transcription of ribosomal protein genes involves a YEATS family protein in Cryptococcus deneoformans

期刊: FEMS YEAST RESEARCH, 2021; 21 (1)

Epigenetic marks or post-translational modifications on histones have important regulatory roles in gene expression in eukaryotic organisms. The epige......

Improving isobutanol tolerance and titers through EMS mutagenesis in Saccharomyces cerevisiae

期刊: FEMS YEAST RESEARCH, 2021; 21 (2)

Improving yeast tolerance toward isobutanol is a critical issue enabling high-titer industrial production. Here, we used EMS mutagenesis to screen Sac......

Rimonabant potentiates the antifungal activity of amphotericin B by increasing cellular oxidative stress and cell membrane permeability

期刊: FEMS YEAST RESEARCH, 2021; 21 (3)

Amphotericin B (AmB) is a very effective antifungal agent, and resistance in clinical isolates is rare. However, clinical treatment with AmB is often ......

Homolog of Saccharomyces cerevisiae SLX4 is required for cell recovery from MMS-induced DNA damage in Candida albicans

期刊: FEMS YEAST RESEARCH, 2021; 21 (2)

SLX4 is a scaffold to coordinate the action of structure-specific endonucleases that are required for homologous recombination and DNA repair. In view......

Discovering and genotyping genomic structural variations by yeast genome synthesis and inducible evolution

期刊: FEMS YEAST RESEARCH, 2020; 20 (2)

Genomic structural variations (SVs) promote the evolution of Saccharomyces cerevisiae, and play an important role in phenotypic diversities. Yeast gen......

Transcription factor Liv4 is required for growth and pathogenesis of Cryptococcus neoformans

期刊: FEMS YEAST RESEARCH, 2020; 20 (3)

Cryptococcus neoformans is an important invasive fungal pathogen that causes life-threatening meningoencephalitis in humans. Its biological and pathog......

Candida albicans infection disturbs the redox homeostasis system and induces reactive oxygen species accumulation for epithelial cell death

期刊: FEMS YEAST RESEARCH, 2020; 20 (4)

Candida albicans is a common pathogenic fungus with high mortality in immunocompromised patients. However, the mechanism by which C. albicans invades ......

The antifungal pipeline: the need is established. Are there new compounds?

期刊: FEMS YEAST RESEARCH, 2020; 20 (4)

Our review summarizes and compares the temporal development (eras) of antifungal drug discovery as well as antibacterial ventures. The innovation gap ......

Rhodosporidium toruloides - A potential red yeast chassis for lipids and beyond

期刊: FEMS YEAST RESEARCH, 2020; 20 (5)

The red yeast Rhodosporidium toruloides naturally produces microbial lipids and carotenoids. In the past decade or so, many studies demonstrated R. to......

Molecular mechanism of the response of Zygosaccharomyces rouxii to D-fructose stress by the glutathione metabolism pathway

期刊: FEMS YEAST RESEARCH, 2020; 20 (5)

Zygosaccharomyces rouxii produces high levels of 4-hydroxy-2,5-dimethyl-3(2H)-furanone in YPD medium supplemented with 120 g/L D-fructose and 180 g/L ......

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