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Nicotinamide phosphoribosyltransferase inhibitor is a novel therapeutic candidate in LPS-induced neutrophil extracellular traps

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (7)

Neutrophil extracellular traps (NETs) are beneficial antibacterial defense structures. However, excessive NETs have also been linked to tissue damage ......

Study of surface activation markers on CD3(-)CD16(+) NK cells and their correlation with clinical manifestations in children with infectious mononucleosis

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (9)

This study aimed to investigate the proportion of surface activation markers on natural killer (NK) cells in children with infectious mononucleosis (I......

The changes of respiratory microbiome between mild and severe asthma patients

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (5)

Due to the increased number of patients suffering from asthma, the mechanism of this disease has been subject to much attention from the public and fi......

Neurotrophic factor levels in the serum and cerebrospinal fluid of neonates infected with human cytomegalovirus

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (9)

Human cytomegalovirus (HCMV) is most likely to damage the central nervous system (CNS) during early embryonic development; however, the early neurodev......

cydA, spdC, and mroQ are novel genes involved in the plasma coagulation of Staphylococcus aureus

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (9)

Coagulation is a critical pathogenic process in Staphylococcus aureus. Although the agglutination of S. aureus has been studied for a long time, the g......

beta-Glycyrrhetinic acid inhibits the bacterial growth and biofilm formation by supragingival plaque commensals

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (9)

beta-Glycyrrhetinic acid (BGA) is a natural antibacterial agent. Previous studies reported that BGA has antibacterial effects against several bacteria......

Prospective study of ALDH1A1 gene polymorphisms associated with antituberculosis drug-induced liver injury in western Chinese Han population

期刊: MICROBIOLOGY AND IMMUNOLOGY, ; ()

Antituberculosis drug-induced liver injury (ATDILI) has received increasing attention globally, which may limit the effectiveness of antituberculosis ......

Influenza A virus protein PA-X suppresses host Ankrd17-mediated immune responses

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (1)

Influenza A virus (IAV) PA-X is a critical ribonuclease protein involved in host cell shutoff but its role in modulating the host immune response to I......

CXC chemokine ligand 5 (CXCL5) disrupted the permeability of human brain microvascular endothelial cells via regulating p38 signal

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2021; 65 (1)

The ischemia-reperfusion-induced damage in human brain microvascular endothelial cells (BMECs) is associated with disruption of the blood-brain barrie......

Virucidal activity and the antiviral mechanism of acidic polysaccharides against Enterovirus 71 infection in vitro

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2020; 64 (3)

Enterovirus 71 (EV71) is the predominant pathogen for severe hand, foot, and mouth disease (HFMD) in children younger than 5 years, and currently no e......

Transforming growth factor-beta promotes the function of HIV-specific CXCR5(+)CD8 T cells

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2020; 64 (6)

HIV replication can be inhibited by CXCR5(+)CD8 T cells (follicular cytotoxic T cell [TFC]) which transfer into B-cell follicles where latent HIV infe......

Therapeutic effect of omega-3 fatty acids on T cell-mediated autoimmune diseases

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2020; 64 (8)

The present study was to demonstrate that the G protein coupled receptors serve as targets for the treatment of autoimmune disease such as rheumatoid ......

Domain I of hepatitis C virus NS5A associates with ACBD3 in a genotype-dependent manner

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2020; 64 (8)

Previously, it was found that the hepatitis C virus NS5A interacted with ACBD3 in a genotype-dependent manner. However, the region in NS5A responsible......

Resveratrol ameliorates thymus senescence changes in D-galactose induced mice

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2020; 64 (9)

The thymic microenvironment plays an important role in the development of T cells. A decrease of thymic epithelial cells is the main cause of age-rela......

Yersinia YopT inhibits RLH-mediated NF-kappa B and IRF3 signal transduction

期刊: MICROBIOLOGY AND IMMUNOLOGY, 2020; 64 (11)

The Gram-negative bacterial pathogenYersiniadelivers six effector proteins into the host cells to block the host innate immune response. One of the ef......

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