期刊: GENES TO CELLS, 2022; 27 (5)
Base excision repair (BER) removes damaged bases by generating single-strand breaks (SSBs), gap-filling by DNA polymerase beta (POL beta), and reseali......
期刊: GENES TO CELLS, 2021; 26 (9)
Autophagy in dopamine (DA) neurons is concerned to be associated with Parkinson's disease (PD), but the detailed mechanism remains unknown. Herein, we......
期刊: GENES TO CELLS, 2021; 26 (9)
There are currently no treatments for salivary gland diseases, making it vital to understand signaling mechanisms operating in acinar and ductal cells......
As the sentinels of innate and adaptive immune system, dendritic cells (DCs) have been considered to hold a great promise for medical application. Amo......
期刊: GENES TO CELLS, 2020; 25 (7)
Nasopharyngeal carcinoma (NPC) is a malignant tumor in nasopharynx tissues and lacks effective treatment strategies. Dysregulation of distal-less home......
期刊: GENES TO CELLS, 2020; 25 (1)
In Bombyx mori, there are more than 30 mutant strains exhibiting the translucent larval skin resulting from a decrease in the uric acid content in epi......
期刊: GENES TO CELLS, 2020; 25 (6)
Microglial inflammation is identified as a key process associated with Parkinson's disease (PD) pathogenesis. Our previous study showed that miR-29c-3......
The intercalated disk (ID), a highly organized adhesion structure connecting neighboring cardiomyocytes, fulfills mechanical and electrical signaling ......
The E. coli single-stranded DNA-binding protein (SSB) is essential to viability. It plays key roles in DNA metabolism where it binds to nascent single......
期刊: GENES TO CELLS, 2019; 24 (4)
Primitive endoderm (PrE)-related cell lines (XEN, pXEN and nEnd cells) show key features of the PrE. By transcriptome analysis, we show: (a) Compared ......
期刊: GENES TO CELLS, 2018; 23 (1)
CD147 is highly expressed in hepatocellular carcinoma (HCC) and associated with the invasion and metastasis of HCC. The efficacy of I-131-metuximab (I......
期刊: GENES TO CELLS, 2018; 23 (7)
The Fourth Asia-Pacific Drosophila Research Conference (APDRC4) was held at the convention center of Osaka University, Osaka, Japan, on May 8-11, 2017......
期刊: GENES TO CELLS, 2018; 23 (9)
PERK and GCN2 are eIF2 kinases known to mediate the effects of ER stress and respond to an array of diverse stress stimuli. Previously, we reported th......
期刊: GENES TO CELLS, 2018; 23 (10)
The B-cell receptor (BCR) transmits a tonic survival signal in the absence of antigen stimulation and an antigen-triggered survival signal. Mature B c......
期刊: GENES TO CELLS, 2017; 22 (10)
In eukaryotic cells, a surveillance mechanism, the S phase checkpoint, detects and responds to insults that challenge chromosomal replication, arresti......