期刊: ARCHIV DER PHARMAZIE, 2021; 354 (7)
Toad venom, a traditional natural medicine, has been used for hundreds of years in China for treating different diseases. Many studies have been perfo......
期刊: ARCHIV DER PHARMAZIE, 2021; 354 (9)
A novel protein (D1 component) was purified from Boletus bicolor by ion-exchange chromatography and gel chromatography on a HiTrap (TM) Q HP column, a......
期刊: ARCHIV DER PHARMAZIE, 2021; 354 (9)
A series of 5-amino-1-N-substituted-imidazole-4-carboxylate building blocks was synthesized and assayed for their antiproliferative potential against ......
期刊: ARCHIV DER PHARMAZIE, 2021; 354 (8)
The abnormal expression of lysine-specific histone demethylase 1 (LSD1) is associated with different cancer types, and LSD1 inhibitory activity seems ......
期刊: ARCHIV DER PHARMAZIE, 2021; 354 (9)
Cancer remains one of the major causes of death worldwide despite the encouraging breakthroughs in the discovery of novel chemotherapeutic agents in r......
期刊: ARCHIV DER PHARMAZIE, 2021; 354 (8)
Platycodin D (PD) is the active metabolite of Platycodon grandiflorum. The main purpose of this study was to develop and evaluate a water-in-oil (W/O)......
期刊: ARCHIV DER PHARMAZIE, ; ()
Continuing our studies on NO-donating ursolic acid-benzylidene derivatives as potential antitumor agents, we designed and synthesized a series of new ......
期刊: ARCHIV DER PHARMAZIE, ; ()
Adenosine monophosphate-activated protein kinase (AMPK) plays a key role in maintaining whole-body homeostasis and has been regarded as a therapeutic ......
期刊: ARCHIV DER PHARMAZIE, 2020; 353 (10)
As the growth in resistance to bacterial infection treatments poses a grave threat to global health in the 21st century, there is a constant need to e......
期刊: ARCHIV DER PHARMAZIE, 2020; 353 (9)
The transporting kinetics and metabolic kinetics of ursolic acid were studied in transgenic cell models. Then, the pharmacokinetics features of ursoli......
期刊: ARCHIV DER PHARMAZIE, 2020; 353 (10)
In this study, novel 2,4-diaminopyrimidine derivatives targeting p21-activated kinase 4 (PAK4) were discovered and evaluated for their biological acti......
期刊: ARCHIV DER PHARMAZIE, 2020; 353 (10)
The emergence and worldwide spread of drug-resistant bacteria have already posed a serious threat to human life, creating the urgent need to develop p......
期刊: ARCHIV DER PHARMAZIE, 2020; 353 (12)
A series of polysubstituted pyrrolidines obtained via ruthenium-catalyzed cascade cyclization of diazo pyruvates and anilines as well as their corresp......
期刊: ARCHIV DER PHARMAZIE, 2020; 353 (11)
Malaria, caused by the genusPlasmodium, remains a global public health concern. It is estimated by the World Health Organization that over 40% of the ......
期刊: ARCHIV DER PHARMAZIE, 2020; 353 (3)
The isatin framework is a useful template for the development of novel anticancer agents. This is exemplified by the fact that several isatin-based an......