期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (5)
Alteration of bladder morphology and function was the most important consequence of bladder outlet obstruction (BOO). Using a rat model of partial BOO......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (4)
Stimulator of interferon genes (STING) is an important adaptor in cytosolic DNA-sensing pathways. A recent study found that the deletion of STING amel......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 321 (2)
Oxygen homeostasis disturbances play a critical role in the pathogenesis of acute kidney injury (AKI). The transcription factor hypoxia-inducible fact......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (5)
Retinoid acid (RA) is synthesized mainly in the fiver and has multiple functions in development, cell differentiation and proliferation, and regulatio......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 321 (1)
High-dietary K+ (HK) intake inhibits basolateral Kir4.1/Kir5.1 activity in the distal convoluted tubule (DCT), and HK-induced inhibition of Kir4.1/Kir......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (4)
Regulated cell death (RCD), distinct from accidental cell death, refers to a process of well-controlled programmed cell death with well-defined pathol......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (6)
High sodium (HS) intake inhibited epithelial Na+ channel (ENaC) in the aldosterone-sensitive distal nephron and Na+ -Cl- cotransporter (NCC) by suppre......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (5)
Neural precursor cell expressed developmentally downregulated protein 4-2 (Nedd4-2) regulates the expression of Kir4.1, thiazide-sensitive NaCl cotran......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (6)
Pigs represent a potentially attractive model for medical research. Similar body size and physiological patterns of kidney injury that more closely mi......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 321 (1)
The renal nephron consists of a series of distinct cell types that function in concert to maintain fluid and electrolyte balance and blood pressure. T......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (2)
Renal arteriolar tone depends considerably on the dilatory action of nitric oxide (NO) via activation of soluble guanylyl cyclase (sGC) and cGMP actio......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (3)
Peritoneal dialysis (PD)-related peritoneal fibrosis (PF) is characterized by progressive extracellular matrix (ECM) accumulation in peritoneal mesoth......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (3)
Renal ischemia-reperfusion (I/R) injury is associated with markedly reduced protein expression of aquaporins (AQPs). Membrane G protein-coupled bile a......
期刊: AMERICAN JOURNAL OF PHYSIOLOGY-RENAL PHYSIOLOGY, 2021; 320 (3)
Primary hyperoxaluria type 1 (PH1) is a severe inherited disorder caused by a genetic defect in alanine-glyoxylate aminotransferase (AGXT), which resu......