期刊: IET SYSTEMS BIOLOGY, 2022; 16 (1)
Stroke is one of the leading causes of patients' death and long-term disability worldwide, and ischaemic stroke (IS) accounts for nearly 80% of all st......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (2)
RYR2 mutation is clinically frequent in non-small cell lung cancer (NSCLC) with its function being elusive. We downloaded lung squamous cell carcinoma......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (5)
This study aims to discover the genetic modules that distinguish glioblastoma multiforme (GBM) from low-grade glioma (LGG) and identify hub genes. A c......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (1)
Identification of drug-target interactions (DTIs) has great practical importance in the drug discovery process for known diseases. However, only a sma......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (3-4)
Acute paraquat poisoning is due to the extremely severe toxicity of paraquat. After paraquat enters the human body, it will cause rapid changes in the......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (1)
Liver hepatocellular carcinoma (LIHC) comprises most cases of liver cancer with a poor prognosis. N-6-methyladenosine (m6A) plays important biological......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (2)
Colon cancer (CC) is one of the most commonly diagnosed tumours worldwide. Single-cell RNA sequencing (scRNA-seq) can accurately reflect the heterogen......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (3-4)
Prenatal karyotype diagnosis is important to determine if the foetus has genetic diseases and some congenital diseases. Chromosome classification is a......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (6)
The development of sequencing technology has promoted the expansion of cancer genome data. It is necessary to identify the pathogenesis of cancer at t......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (3-4)
The cingulate cortex is part of the conserved limbic system, which is considered as a hub of emotional and cognitive control. Accumulating evidence su......
期刊: IET SYSTEMS BIOLOGY, 2022; 16 (2)
N6-methyladenosine (m(6)A) RNA methylation is correlated with carcinogenesis and dynamically possessed through the m(6)A RNA methylation regulators. T......
期刊: IET SYSTEMS BIOLOGY, 2021; 15 (3)
Ischemic stroke (IS) is one of the major causes of death and disability worldwide. However, the specific mechanism of gene interplay and the biologica......
期刊: IET SYSTEMS BIOLOGY, 2021; 15 (4)
The bistable Rb-E2F gene regulatory network plays a central role in regulating cellular proliferation-quiescence transition. Based on Gillespie's chem......
期刊: IET SYSTEMS BIOLOGY, 2021; 15 (4)
Natural products have been widely used in the treatment of type 2 diabetes (T2D). However, their mechanisms are often obscured due to multi-components......
期刊: IET SYSTEMS BIOLOGY, 2021; 15 (5)
Accurate detection of chronic kidney disease (CKD) plays a pivotal role in early diagnosis and treatment. Measured glomerular filtration rate (mGFR) i......