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A Predictive Score of Antitumour Activity of Novel Agents in Cancer Patients Treated in Early Phase Studies

期刊: ONCOLOGY, ; ()

Introduction: Phase I trials aim to determine the maximum-tolerated dose of a particular drug while minimizing the number of patients exposed to eithe......

Predictors of Nodal Pathological Complete Response in Asian Women with Stage II-III Node-Positive Breast Cancer

期刊: ONCOLOGY, ; ()

Background: Neoadjuvant chemotherapy (NAC) is increasingly used to treat node-positive (N+) breast cancer. Predictors of nodal pathological complete r......

BUB1B Overexpression Is an Independent Prognostic Marker and Associated with CD44, p53, and PD-L1 in Renal Cell Carcinoma

期刊: ONCOLOGY, 2021; 99 (4)

Introduction: BUB1 mitotic checkpoint serine/threonine kinase B encoded by BUB1B gene is a member of the spindle assembly checkpoint family. Several r......

Diagnostic Capability of Cerebrospinal Fluid-Placental Alkaline Phosphatase Value in Intracranial Germ Cell Tumor

期刊: ONCOLOGY, 2021; 99 (1)

Objective: Most types of intracranial germ cell tumors (IGCTs) are sensitive to chemoradiation. However, biopsy specimens are usually small and thus c......

Decision-Making Analysis for Hyperthermic Intraperitoneal Chemotherapy in Ovarian Cancer: A Survey by the Executive Committee of the Peritoneal Surface Oncology Group International (PSOGI)

期刊: ONCOLOGY, 2021; 99 (1)

Objectives: To assess the individual treatment strategies among international experts in peritoneal carcinosis, specifically their decision-making in ......

Expression and Clinical Significance of POLR1D in Colorectal Cancer

期刊: ONCOLOGY, 2020; 98 (3)

Purpose: RNA polymerase I subunit D (POLR1D) is involved in the synthesis of ribosomal RNA precursors and small RNAs, but its mechanism in the develop......

Pathogenic Germline Mutations in Chinese Patients with Gastric Cancer Identified by Next-Generation Sequencing

期刊: ONCOLOGY, 2020; 98 (8)

Background:Gastric cancer (GC) is one of the leading causes of cancer death in China, while the nature of genetic factors related to GC has not been w......

TUBB3 Is Associated with High-Grade Histology, Poor Prognosis, p53 Expression, and Cancer Stem Cell Markers in Clear Cell Renal Cell Carcinoma

期刊: ONCOLOGY, 2020; 98 (10)

Background:beta III-Tubulin, encoded by theTUBB3gene, is a microtubule protein. Several studies have shown that overexpression of TUBB3 is linked to p......

Clinically Observed Estrogen Receptor Alpha Mutations within the Ligand-Binding Domain Confer Distinguishable Phenotypes

期刊: ONCOLOGY, 2018; 94 (3)

Objective: Twenty to fifty percent of estrogen receptor-positive (ER+) metastatic breast cancers express mutations within the ER ligand-binding domain......

JIF:2.28

Expression and Clinical Implication of Autophagy-Associated Protein p62 in Osteosarcoma

期刊: ONCOLOGY, 2018; 95 (1)

Purpose: Recent studies highlight the role of autophagy in cancer tumorigenesis, recurrence, metastasis, and chemoresistance. p62 is an adapter protei......

JIF:2.28

DNA-Sensing and Nuclease Gene Expressions as Markers for Colorectal Cancer Progression

期刊: ONCOLOGY, 2017; 92 (2)

Objective: Oncogene-driven stress-related DNA damage has been observed in lesions of colon cancer. Furthermore, DNA sensors and nucleases are stimulat......

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