期刊: ONCOLOGY, ; ()
Introduction: Phase I trials aim to determine the maximum-tolerated dose of a particular drug while minimizing the number of patients exposed to eithe......
期刊: ONCOLOGY, ; ()
Background: Neoadjuvant chemotherapy (NAC) is increasingly used to treat node-positive (N+) breast cancer. Predictors of nodal pathological complete r......
Introduction: BUB1 mitotic checkpoint serine/threonine kinase B encoded by BUB1B gene is a member of the spindle assembly checkpoint family. Several r......
Objective: Most types of intracranial germ cell tumors (IGCTs) are sensitive to chemoradiation. However, biopsy specimens are usually small and thus c......
Objectives: To assess the individual treatment strategies among international experts in peritoneal carcinosis, specifically their decision-making in ......
Purpose: RNA polymerase I subunit D (POLR1D) is involved in the synthesis of ribosomal RNA precursors and small RNAs, but its mechanism in the develop......
Background:Gastric cancer (GC) is one of the leading causes of cancer death in China, while the nature of genetic factors related to GC has not been w......
Background:beta III-Tubulin, encoded by theTUBB3gene, is a microtubule protein. Several studies have shown that overexpression of TUBB3 is linked to p......
Objective: Twenty to fifty percent of estrogen receptor-positive (ER+) metastatic breast cancers express mutations within the ER ligand-binding domain......
Purpose: Recent studies highlight the role of autophagy in cancer tumorigenesis, recurrence, metastasis, and chemoresistance. p62 is an adapter protei......
Objective: Oncogene-driven stress-related DNA damage has been observed in lesions of colon cancer. Furthermore, DNA sensors and nucleases are stimulat......