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Direct and pleiotropic effects of the Masou Salmon Delta-5 Desaturase transgene in F1 channel catfish (Ictalurus punctatus)

期刊: TRANSGENIC RESEARCH, 2021; 30 (2)

Channel catfish (Ictalurus punctatus) is the primary culture species in the US along with its hybrid made with male blue catfish, I. furcatus. In an e......

Efficiency comparison of B6(Cg)-Tyr(c-2j) /J and C57BL/6NTac embryos as hosts for the generation of knockout mice

期刊: TRANSGENIC RESEARCH, 2021; 30 (3)

Careful selection of the host embryo is critical to the efficient production of knockout (KO) mice when injecting mouse embryonic stem (mES) cells int......

Generation and identification of endothelial-specific Hrh2 knockout mice

期刊: TRANSGENIC RESEARCH, ; ()

Histamine H-2 receptor (HRH2) is closely associated with the development of cardiovascular and cerebrovascular diseases. However, systematic Hrh2 knoc......

Genetic engineering to improve essential and conditionally essential amino acids in maize: transporter engineering as a reference

期刊: TRANSGENIC RESEARCH, ; ()

Ruminants and humans are unable to synthesize essential amino acids (EAAs) and conditionally essential amino acids (CEAAs) under normal conditions and......

Target-specific mutations efficiency at multiple loci of CRISPR/Cas9 system using one sgRNA in soybean

期刊: TRANSGENIC RESEARCH, 2021; 30 (1)

Soybean has a palaeopolyploid genome with nearly 75% of the genes present in multiple copies. Although the CRISPR/Cas9 system has been employed in soy......

Methylation silencing and reactivation of exogenous genes in lentivirus-mediated transgenic mice

期刊: TRANSGENIC RESEARCH, 2021; 30 (1)

Taking advantage of their ability to integrate their genomes into the host genome, lentiviruses have been used to rapidly produce transgenic mice in b......

Effect of low VEGF on lung development and function

期刊: TRANSGENIC RESEARCH, 2021; 30 (1)

Vascular endothelial growth factor (VEGF) is important for lung development and function but ideal mouse models are limited to decipher the quantitati......

Efficient identification of genomic insertions and flanking regions through whole-genome sequencing in three transgenic soybean events

期刊: TRANSGENIC RESEARCH, 2021; 30 (1)

Genomic insertions and flanking regions of transgenes in host genomes constitute a critical component of precise molecular characterization and event-......

Fitness of F1 hybrids between 10 maternal wild soybean populations and transgenic soybean

期刊: TRANSGENIC RESEARCH, 2021; 30 (1)

The releasing of transgenic soybeans (Glycine max (L.) Merr.) into farming systems raises concerns that transgenes might escape from the soybeans via ......

Overexpression of the chitinase gene CmCH1 from Coniothyrium minitans renders enhanced resistance to Sclerotinia sclerotiorum in soybean

期刊: TRANSGENIC RESEARCH, 2020; 29 (2)

Pathogenic fungi represent one of the major biotic stresses for soybean production across the world. Sclerotinia sclerotiorum, the causal agent of Scl......

Precise editing of myostatin signal peptide by CRISPR/Cas9 increases the muscle mass of Liang Guang Small Spotted pigs

期刊: TRANSGENIC RESEARCH, 2020; 29 (1)

Myostatin (MSTN), a member of the transforming growth factor-beta superfamily, is a negative regulator of muscle growth and development. Disruption of......

Altered sucrose metabolism and plant growth in transgenic Populus tomentosa with altered sucrose synthase PtSS3

期刊: TRANSGENIC RESEARCH, 2020; 29 (1)

Improvement of wood quality is an important focus of forest genetics and breeding research. Sucrose synthase (SS) catalyzes the reaction of sucrose an......

Enhanced skeletal muscle growth in myostatin-deficient transgenic pigs had improved glucose uptake in stretozotocin-induced diabetes

期刊: TRANSGENIC RESEARCH, 2020; 29 (2)

The size of skeletal muscle mass plays a significant role in glucose uptake in healthy and diabetic human subjects. Previously, we have generated myos......

Genetic removal of the CH1 exon leads to the production of hypofunctional heavy chain-only IgG2a in rats

期刊: TRANSGENIC RESEARCH, 2020; 29 (2)

Despite great values in many applications, heavy chain-only antibodies (HcAbs) are naturally only produced in camelids and sharks, which are not easy ......

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