Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond

期刊： PHARMACOLOGICAL REVIEWS, 2020; 72 (2)

Ubiquitin (UB) transfer cascades con-sisting of E1, E2, and E3 enzymes constitute a complex network that regulates a myriad of biologic processes by m......

Targeting Foam Cell Formation in Atherosclerosis: Therapeutic Potential of Natural Products

期刊： PHARMACOLOGICAL REVIEWS, 2019; 71 (4)

Foam cell formation and further accumulation in the subendothelial space of the vascular wall is a hallmark of atherosclerotic lesions. Targeting foam......

JIF：18.89

RAL GTPases: Biology and Potential as Therapeutic Targets in Cancer

期刊： PHARMACOLOGICAL REVIEWS, 2018; 70 (1)

More than a hundred proteins comprise the RAS superfamily of small GTPases. This family can be divided into RAS, RHO, RAB, RAN, ARF, and RAD subfamili......

JIF：18.89