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PDGFD switches on stem cell endothelial commitment

期刊: ANGIOGENESIS, 2022; 25 (4)

The critical factors regulating stem cell endothelial commitment and renewal remain not well understood. Here, using loss- and gain-of-function assays......

JIF:8.49

Extracellular matrix stiffness controls VEGF(165) secretion and neuroblastoma angiogenesis via the YAP/RUNX2/SRSF1 axis

期刊: ANGIOGENESIS, 2022; 25 (1)

Aberrant variations in angiogenesis have been observed in tumor tissues with abnormal stiffness of extracellular matrix (ECM). However, it remains lar......

JIF:8.49

Copper stress impairs angiogenesis and lymphangiogenesis during zebrafish embryogenesis by down-regulating pERK1/2-foxm1-MMP2/9 axis and epigenetically regulating ccbe1 expression

期刊: ANGIOGENESIS, 2022; 25 (2)

Molecular transport and cell circulation between tissues and organs through blood and lymphatic vessels are essential for physiological homeostasis in......

JIF:8.49

Molecular mechanisms of coronary microvascular endothelial dysfunction in diabetes mellitus: focus on mitochondrial quality surveillance

期刊: ANGIOGENESIS, 2022; 25 (3)

Coronary microvascular endothelial dysfunction is both a culprit and a victim of diabetes, and can accelerate diabetes-related microvascular and macro......

JIF:8.49

Peritumoral B cells drive proangiogenic responses in HMGB1-enriched esophageal squamous cell carcinoma

期刊: ANGIOGENESIS, 2022; 25 (2)

Several B-cell subsets with distinct functions and polarized cytokine profiles that extend beyond antibody production have been reported in different ......

JIF:8.49

Successful management of lung adenocarcinoma with ALK/EGFR co-alterations and PD-L1 over-expression by bevacizumab combined with chemotherapy

期刊: ANGIOGENESIS, 2022; 25 (1)

Anaplastic lymphoma kinase (ALK)/epidermal growth factor receptor (EGFR) co-alterations in adenocarcinomas are rare and no therapeutic consensus is re......

JIF:8.49

TAK1 signaling is a potential therapeutic target for pathological angiogenesis

期刊: ANGIOGENESIS, 2021; 24 (3)

Angiogenesis plays a critical role in both physiological responses and disease pathogenesis. Excessive angiogenesis can promote neoplastic diseases an......

Endothelial cell plasticity at the single-cell level

期刊: ANGIOGENESIS, 2021; 24 (2)

The vascular endothelium is characterized by a remarkable level of plasticity, which is the driving force not only of physiological repair/remodeling ......

YAP promotes ocular neovascularization by modifying PFKFB3-driven endothelial glycolysis

期刊: ANGIOGENESIS, ; ()

Ocular neovascularization is the leading cause of vision impairment in a variety of ocular diseases, such as age-related macular degeneration and reti......

A novel lymphatic pattern promotes metastasis of cervical cancer in a hypoxic tumour-associated macrophage-dependent manner

期刊: ANGIOGENESIS, ; ()

Lymphatic remodelling in the hypoxic tumour microenvironment (TME) is critically involved in the metastasis of cervical squamous cell carcinoma (CSCC)......

Loss of endothelial glucocorticoid receptor promotes angiogenesis via upregulation of Wnt/beta-catenin pathway

期刊: ANGIOGENESIS, ; ()

Objective The glucocorticoid receptor (GR) is a member of the nuclear receptor family that controls key biological processes in the cardiovascular sys......

New insights into the role of mitochondria in cardiac microvascular ischemia/reperfusion injury

期刊: ANGIOGENESIS, 2020; 23 (3)

As reperfusion therapies have become more widely used in acute myocardial infarction patients, ischemia-induced myocardial damage has been markedly re......

Apatinib as targeted therapy for advanced bone and soft tissue sarcoma: a dilemma of reversing multidrug resistance while suffering drug resistance itself

期刊: ANGIOGENESIS, 2020; 23 (3)

Bone and soft tissue sarcomas are rare malignant tumors originated from mesenchymal tissues. They harbor more than 50 distinct subtypes and differ in ......

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