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First Glimpse of Gut Microbiota of Quarantine Insects in China

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (2)

Quarantine insects are economically important pests that frequently invade new habitats. A rapid and accurate monitoring method to trace the geographi......

Phosphoproteomics Reveals the AMPK Substrate Network in Response to DNA Damage and Histone Acetylation

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (4)

AMP-activated protein kinase (AMPK) is a conserved energy sensor that plays roles in diverse biological processes via phosphorylating various substrat......

Epithelial Cells in 2D and 3D Cultures Exhibit Large Differences in Higher-order Genomic Interactions

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (1)

Recent studies have characterized the genomic structures of many eukaryotic cells, often focusing on their relation to gene expression. However, these......

FertilityOnline: A Straightforward Pipeline for Functional Gene Annotation and Disease Mutation Discovery

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (3)

Exploring the genetic basis of human infertility is currently under intensive investigation. However, only a handful of genes have been validated in a......

PHISDetector: A Tool to Detect Diverse In Silico Phage-host Interaction Signals for Virome Studies

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (3)

Phage-microbe interactions are appealing systems to study coevolution, and have also been increasingly emphasized due to their roles in human health, ......

KaKs_Calculator 3.0: Calculating Selective Pressure on Coding and Non-coding Sequences

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (3)

KaKs_Calculator 3.0 is an updated toolkit that is capable of calculating selective pressure on both coding and non-coding sequences. Similar to the no......

Global Profiling of 2-hydroxyisobutyrylome in Common Wheat

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (4)

As a novel post-translational modification (PTM), lysine 2-hydroxyisobutyrylation (Khib) is considered to regulate gene transcriptional activities in ......

Resequencing 250 Soybean Accessions: New Insights into Genes Associated with Agronomic Traits and Genetic Networks

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (1)

The limited knowledge of genomic diversity and functional genes associated with the traits of soybean varieties has resulted in slow progress in breed......

Over 50,000 Metagenomically Assembled Draft Genomes for the Human Oral Microbiome Reveal New Taxa

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (2)

The oral cavity of each person is home to hundreds of bacterial species. While taxa for oral diseases have been studied using culture-based characteri......

CircR2Disease v2.0: An Updated Web Server for Experimentally Validated circRNA-disease Associations and Its Application

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (3)

With accumulating dysregulated circular RNAs (circRNAs) in pathological processes, the regulatory functions of circRNAs, especially circRNAs as microR......

Comparative Secretome Analysis of Magnaporthe oryzae Identified Proteins Involved in Virulence and Cell Wall Integrity

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (4)

Plant fungal pathogens secrete numerous proteins into the apoplast at the plant-fungus contact sites to facilitate colonization. However, only a few s......

Common Postzygotic Mutational Signatures in Healthy Adult Tissues Related to Embryonic Hypoxia

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (1)

Postzygotic mutations are acquired in normal tissues throughout an individual's lifetime and hold clues for identifying mutagenic factors. Here, we in......

Genomic Perspectives on the Emerging SARS-CoV-2 Omicron Variant

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (1)

A new variant of concern for SARS-CoV-2, Omicron (B.1.1.529), was designated by the World Health Organization on November 26, 2021. This study analyze......

Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Experimental Ulcerative Colitis Mice

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (2)

Ulcerative colitis (UC) is a chronic inflammatory bowel disease caused by many factors including colonic inflammation and microbiota dysbiosis. Previo......

Exploration of Target Spaces in the Human Genome for Protein and Peptide Drugs

期刊: GENOMICS PROTEOMICS & BIOINFORMATICS, 2022; 20 (4)

After decades of development, protein and peptide drugs have now grown into a major drug class in the marketplace. Target identification and validatio......

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