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Extracellular vesicles for ischemia/reperfusion injury-induced acute kidney injury: a systematic review and meta-analysis of data from animal models

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Acute kidney injury (AKI) induced by ischemia/reperfusion injury significantly contribute to the burden of end-stage renal disease. Extrac......

Effects of different kinds of anti-Alzheimer's disease drugs on cognitive improvement: protocol for a systematic review and network meta-analysis of phase III clinical trials

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Alzheimer's disease is a neurodegenerative disease characterized by progressive cognitive decline and dysfunction of independent living ab......

Efficacy and safety of blood derivatives therapy in Alzheimer's disease: a systematic review and meta-analysis

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Blood derivatives therapy is a conventional clinical treatment, while the treatment for Alzheimer's disease (AD) is relatively novel. To p......

Survival benefits from neoadjuvant treatment in gastric cancer: a systematic review and meta-analysis

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Surgery is the main treatment option for patients with local gastric cancer. However, surgery alone is usually not sufficient for stomach ......

Lapatinib and lapatinib plus trastuzumab therapy versus trastuzumab therapy for HER2 positive breast cancer patients: an updated systematic review and meta-analysis

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Introduction: Trastuzumab, as the gold standard for HER2-positive BC treatment, was the first-line HER2 targeted drug. However, some studies reported ......

The effectiveness of virtual reality for rehabilitation of Parkinson disease: an overview of systematic reviews with meta-analyses

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: An increasing number of systematic reviews (SRs) and meta-analyses (MAs) of clinical trials have begun to investigate the effects of virtu......

Anticancer effects of disulfiram: a systematic review of in vitro, animal, and human studies

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background and objectives: Cancer morbidity and mortality rates remain high, and thus, at present, considerable efforts are focused on finding drugs w......

Prediction models for breast cancer-related lymphedema: a systematic review and critical appraisal

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Purpose: The development of risk prediction models for breast cancer lymphedema is increasing, but few studies focus on the quality of the model and i......

Automation of literature screening using machine learning in medical evidence synthesis: a diagnostic test accuracy systematic review protocol

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Systematic review is an indispensable tool for optimal evidence collection and evaluation in evidence-based medicine. However, the explosi......

Changes in glycaemic control of oral anti-diabetic medications assessed by continuous glucose monitors among patients with type 2 diabetes: a protocol of network meta-analysis

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Continuous glucose monitors (CGMs) can measure interstitial fluid glucose levels to provide comprehensive real-time glucose profile among ......

Efficacy and safety of Tripterygium wilfordii polyglycosides for diabetic kidney disease: an overview of systematic reviews and meta-analyses

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Recently, several systematic reviews (SRs) and meta-analyses (MAs) of Tripterygium wilfordii polyglycoside (TWP) have reported significant......

A comprehensive evaluation between dexmedetomidine and midazolam for intraoperative sedation in the elderly: protocol for a systematic review and meta-analysis of randomized controlled trials

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: The sedative effect of intraoperative sedation in elderly surgery exerts critical influence on the prognosis. Comparison on the safety and......

Oral care for intensive care unit patients without mechanical ventilation: protocol for a systematic review and meta-analysis

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Infection is a common problem and a major cause of morbidity and mortality for patients in intensive care units (ICUs). According to publi......

Systematic review and meta-analysis of candidate gene association studies of benign prostate hyperplasia

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Benign prostate hyperplasia (BPH) is the most common urological problem in elderly males. Recent studies have reported polymorphism in var......

Gut microbiome-targeted therapies in liver cirrhosis: a protocol for systematic review and meta-analysis

期刊: SYSTEMATIC REVIEWS, 2022; 11 (1)

Background: Microbiome-targeted therapies (MTTs), including probiotics, prebiotics, synbiotics, and fecal microbiota transplantation (FMT), have been ......

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