Cancer can arise as a consequence of the accumulation of genomic alterations. Only a small part of driver mutations contributes to cancer development ......
Ubiquitination is one of the most important post-translational modifications which involves in many biological processes. Because mass spectrometry-ba......
Identifying disease-related genes is of importance for understanding of molecule mechanisms of diseases, as well as diagnosis and treatment of disease......
DNA methylation plays an important role in many biological processes and diseases. With the rise of the whole genome bisulfite sequencing technique, a......
Integrative analysis of multiple omics offers the opportunity to uncover coordinated cellular processes acting across different omics layers. The ever......
Biomarker identification aims at finding a set of biological indicators that best discriminate biological samples of different phenotypes. In this pap......
Analyzing disease-disease relationships plays an important role for understanding disease mechanisms and finding alternative uses for a drug. A diseas......
Magnetic resonance imaging (MRI) is one of the most popular techniques in brain science and is important for understanding brain function and neuropsy......
Cumulative experimental studies have demonstrated the critical roles of microRNAs (miRNAs) in the diverse fundamental and important biological process......
Single-cell protein abundance is a fundamental type of information to characterize cell states. Due to high cost and technical barriers, however, dire......
Motivation: Alternative splicing makes significant contributions to functional diversity of transcripts and proteins. Many alternatively spliced gene ......
The survival rate of cancer has increased significantly during the past two decades for breast, prostate, testicular, and colon cancer, while the brai......
The effective and accurate diagnosis of Alzheimer?s disease (AD), especially in the early stage (i.e., mild cognitive impairment (MCI)) remains a big ......
