Baidu
map
筛选条件 共查询到388条结果
排序方式
Distinct states of proinsulin misfolding in MIDY

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (16)

A precondition for efficient proinsulin export from the endoplasmic reticulum (ER) is that proinsulin meets ER quality control folding requirements, i......

Neurovascular regulation in diabetic retinopathy and emerging therapies

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (16)

Diabetic retinopathy (DR) is the leading cause of vision loss in working adults in developed countries. The disease traditionally classified as a micr......

The Na-x (SCN7A) channel: an atypical regulator of tissue homeostasis and disease

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (14)

Within an articulately characterized family of ion channels, the voltage-gated sodium channels, exists a black sheep, SCN7A (Na-x). Na-x, in contrast ......

AP-1 activity is a major barrier of human somatic cell reprogramming

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (15)

Human induced pluripotent stem cells (iPSCs) technology has been widely applied to cell regeneration and disease modeling. However, most mechanism of ......

Biogenesis, physiological functions and potential applications of extracellular vesicles in substance use disorders

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (11)

Substance use disorder (SUD) is a growing health problem that affects several millions of people worldwide, resulting in negative socioeconomic impact......

BCL2L13: physiological and pathological meanings

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (6)

BCL2L13 is a BCL2-like protein. It has been discovered for two decades, now on the way to be a hotspot of research with its physiological and patholog......

The role of metabolic reprogramming in tubular epithelial cells during the progression of acute kidney injury

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (15)

Acute kidney injury (AKI) is one of the most common clinical syndromes. AKI is associated with significant morbidity and subsequent chronic kidney dis......

Compartmentalized replication organelle of flavivirus at the ER and the factors involved

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (11)

Flaviviruses are positive-sense single-stranded RNA viruses that pose a considerable threat to human health. Flaviviruses replicate in compartmentaliz......

Mobius strip in pancreatic cancer: biogenesis, function and clinical significance of circular RNAs

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (17-18)

Pancreatic cancer (PC) is a kind of common digestive system cancer with the worst prognosis for its insidious symptoms and high invasiveness. Circular......

The role of leukocytes in acute ischemic stroke-related thrombosis: a notable but neglected topic

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (17-18)

Ischemic stroke is one of the most serious diseases today, and only a minority of patients are provided with effective clinical treatment. Importantly......

Role and mechanisms of autophagy in lung metabolism and repair

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (12)

Mammalian lungs are metabolically active organs that frequently encounter environmental insults. Stress responses elicit protective autophagy in epith......

Biomechanical cues as master regulators of hematopoietic stem cell fate

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (16)

Hematopoietic stem cells (HSCs) perceive both soluble signals and biomechanical inputs from their microenvironment and cells themselves. Emerging as c......

Epigenetic regulations in mammalian spermatogenesis: RNA-m(6)A modification and beyond

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (11)

Emerging evidence shows that m(6)A, one of the most abundant RNA modifications in mammals, is involved in the entire process of spermatogenesis, inclu......

Cytokine signaling convergence regulates the microglial state transition in Alzheimer's disease

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (10)

Genetic analyses have revealed the pivotal contribution of microglial dysfunctions to the pathogenesis of Alzheimer's disease (AD). Along AD progressi......

Follicular helper T cells: potential therapeutic targets in rheumatoid arthritis

期刊: CELLULAR AND MOLECULAR LIFE SCIENCES, 2021; 78 (12)

Rheumatoid arthritis (RA) is a chronic autoimmune disease with joint and systemic inflammation that is accompanied by the production of autoantibodies......

共388条页码: 1/26页15条/页
Baidu
map
Baidu
map
Baidu
map