期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
Interrupted axons that fail to regenerate mainly cause poor recovery after spinal cord injury (SCI). How neurons epigenetically respond to injury dete......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 21 ()
Cervical cancer is a common female malignancy that is mainly caused by human papillomavirus (HPV) infection. However, the incidence of HPV-negative ce......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
The anti-inflammatory molecule annexin A1 (ANXA1) determines the ultimate fate of retinal ganglion cell (RGC) in glaucoma. Cytoplasmic and extracellul......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 21 ()
The tumorigenicity and toxicity of induced pluripotent stem cells (iPSCs) and their derivatives are major safety concerns in their clinical applicatio......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
As a malignancy of the gastrointestinal tract, gallbladder cancer (GBC) continues to exhibit notable rates of mortality. The current study aimed at in......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
Exosome-derivedmicroRNAs(miRNAs) are potential diagnostic biomarkers. However, little is known about their effectiveness as diagnostic biomarkers of f......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 21 ()
Microglial cell activation and neuroinflammation after intracerebral hemorrhage (ICH) lead to secondary brain damage. Ubiquitin-specific protease 11 (......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
Inducible conditional knockout mice are important tools for studying gene function and disease therapy, but their generation is costly and time-consum......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 21 ()
The emergence of the novel human severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) has led to the pandemic of coronavirus disease 2019 (COV......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 21 ()
Non-viral platforms can be applied rapidly and cost-effectively for chimeric antigen receptor (CAR)-T cell manufacturing. In the present paper, we des......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
Nasopharyngeal carcinoma (NPC) is one of the most common malignant tumors in Chinese and other Southeast Asians. We aimed to explore the precise mecha......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
Adenosine deaminase (ADA) deficiency is an inborn error of metabolism affecting multiple systems and causing severe combined immunodeficiency. We test......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 21 ()
The increasing demand for adeno-associated virus (AAV) vectors, a result from the surging interest for their potential to cure human genetic diseases ......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 20 ()
We investigated the immunogenic cell death provoked by oxaliplatin (OXA) and the involvement of OXA-induced immunosuppression in colorectal cancer. Im......
期刊: MOLECULAR THERAPY-METHODS & CLINICAL DEVELOPMENT, 2021; 21 ()
Hereditary tyrosinemia type I (HT1) results from the loss of fumarylacetoacetate hydrolase (FAH) activity and can lead to lethal liver injury (LLI). T......