期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
Background Telomere maintenance is crucial for the unlimited proliferation of cancer cells and essential for the "stemness" of multiple cancer cells. ......
期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
We identified a rare missense germline mutation in BARD1 (c.403G>A or p.Asp135Asn) as pathogenic using integrated genomics and transcriptomics prof......
期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
BackgroundThe ovarian hormones estrogen and progesterone (EP) are implicated in breast cancer causation. A specific consequence of progesterone exposu......
期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
Backgrounds In contrast to developed countries, breast cancer in China is characterized by a rapidly escalating incidence rate in the past two decades......
期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
Background MicroRNAs have been reported to participate in tumorigenesis, treatment resistance, and tumor metastasis. Novel microRNAs need to be identi......
期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
Background: Basal-like breast cancers (BLBCs) are a leading cause of cancer death due to their capacity to metastasize and lack of effective therapies......
期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
Background Findings from randomized clinical trials may have limited generalizability to patients treated in routine clinical practice. This study exa......
期刊: BREAST CANCER RESEARCH, 2021; 23 (1)
Purpose To evaluate weight change patterns over time following the diagnosis of breast cancer and to examine the association of post-diagnosis weight ......
期刊: BREAST CANCER RESEARCH, 2020; 22 (1)
Background Breast cancer stem cells (BCSCs) are typically seed cells of breast tumor that initiate and maintain tumor growth. MiR-7, as a cancer inhib......
期刊: BREAST CANCER RESEARCH, 2020; 22 (1)
Background Breast cancer is rare in men, but management is focused on tumor characteristics commonly found in female breast cancer. The tumor microenv......
期刊: BREAST CANCER RESEARCH, 2020; 22 (1)
Triple-negative breast cancer (TNBC), a specific subtype of breast cancer that does not express estrogen receptor (ER), progesterone receptor (PR), or......
期刊: BREAST CANCER RESEARCH, 2020; 22 (1)
Background Metaplastic breast carcinoma (MBC) is a rare histological type of breast cancer, which commonly shows resistance to standard therapies and ......
期刊: BREAST CANCER RESEARCH, 2020; 22 (1)
Background Sunitinib, a receptor tyrosine kinase (RTK) inhibitor that targets multiple receptors such as vascular endothelial growth factor receptors ......
期刊: BREAST CANCER RESEARCH, 2020; 22 (1)
Background Although breast cancer mortality is a result of distant recurrences associated with the establishment of tumor dormancy, current clinical p......
期刊: BREAST CANCER RESEARCH, 2020; 22 (1)
Metaplastic breast cancer (MpBC) is an exceedingly rare breast cancer variant that is therapeutically challenging and aggressive. MpBC is defined by t......