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Analogs of imine resveratrol alleviate oxidative stress-induced neurotoxicity in PC12 cells via activation of Nrf2

期刊: FEBS OPEN BIO, 2021; 11 (8)

Oxidative stress is closely associated with neurodegenerative, cardiovascular and metabolic diseases. Resveratrol and related compounds have shown gre......

Improved strategy for jet-in-air cell sorting with high purity, yield, viability, and genome stability

期刊: FEBS OPEN BIO, 2021; 11 (9)

Flow cytometric sorting is a vital tool in biological research and clinical diagnostics. Theoretically, a high-speed jet-in-air sorter is a fluorescen......

Down-regulation of Polo-like kinase 4 (PLK4) induces G1 arrest via activation of the p38/p53/p21 signaling pathway in bladder cancer

期刊: FEBS OPEN BIO, 2021; 11 (9)

Polo-like kinase 4 (PLK4) has been reported to contribute to tumor growth, invasion, and metastasis. However, the role of PLK4 in human bladder cancer......

CSNK2A1-mediated phosphorylation of HMGA2 modulates cisplatin resistance in cervical cancer

期刊: FEBS OPEN BIO, 2021; 11 (8)

The development of chemoresistance reduces the efficacy of anti-cancer drugs. Cervical cancer is still one of the most common cancer types in developi......

Upregulation of ZHX2 predicts poor prognosis and is correlated with immune infiltration in gastric cancer

期刊: FEBS OPEN BIO, 2021; 11 (6)

The transcriptional repressor zinc finger homeobox 2 (ZHX2) is reported to regulate tumor progression in several human cancers, although little is kno......

Dkk1 inhibits malignant transformation induced by Bmi1 via the beta-catenin signaling axis in WB-F344 oval cells

期刊: FEBS OPEN BIO, 2021; 11 (7)

Dickkopf-1 (Dkk1) is an inhibitor of Wnt signaling involved in cancer cell proliferation, apoptosis, and migration and angiogenesis. It was previously......

Inhibition of miR-93-5p promotes osteogenic differentiation in a rabbit model of trauma-induced osteonecrosis of the femoral head

期刊: FEBS OPEN BIO, 2021; 11 (8)

Trauma-induced osteonecrosis of the femoral head (TIONFH) is characterized by femoral head collapse accompanied by degenerative changes of the hip. We......

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