期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (1)
Large tumor suppressor 1 (LATS1) is the key kinase controlling activation of Hippo signalling pathway. Post-translational modifications of LATS1 modul......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (10)
The gut microbiota is involved in host responses to high altitude. However, the dynamics of intestinal microecology and their association with altitud......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (12)
The soybean E1 gene is a major regulator that plays an important role in flowering time and maturity. However, it remains unclear how cultivars carryi......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (2)
Susceptibility of patients with chronic obstructive pulmonary disease (COPD) to cardiovascular autonomic dysfunction associated with exposure to metal......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (2)
Mitochondria, double-membrane organelles, are known to participate in a variety of metabolic and signal transduction pathways. The intermembrane space......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (8)
Leucine-rich repeat containing G protein-coupled receptor 5 (Lgr5), a marker of intestinal stem cells (ISCs), is considered to play key roles in tissu......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (11)
The RNA editing tool CRISPR-CasRx has provided a platform for a range of transcriptome analysis tools and therapeutic approaches with its broad effica......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (10)
Sepsis, defined as life-threatening organ failure caused by a dysregulated host response to severe infection, is a major cause of death among intensiv......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (1)
Apart from their primordial role in protein synthesis, tRNAs can be cleaved to produce tRNA-derived small RNAs (tsRNAs). The biological functions of t......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (6)
Microglia are known to play essential roles in the development, progression and treatment of diverse neurodegenerative diseases in the central nervous......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (1)
Osteoclastogenesis in alveolar bone induced by compression stress triggers orthodontic tooth movement. Compression stress also stimulates angiogenesis......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (1)
The iron oxide nanoparticles (IONPs) that combine the nanozyme activity and magnetothermal properties have attracted significant interest for various ......
期刊: SCIENCE CHINA-LIFE SCIENCES, 2022; 65 (1)
Adenosine-to-inosine (A-to-I) RNA editing is a widespread posttranscriptional modification that has been shown to play an important role in tumorigene......