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Curcumin inhibits cancer progression through regulating expression of microRNAs

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Curcumin, a major yellow pigment and spice in turmeric and curry, is a powerful anti-cancer agent. The anti-tumor activities of curcumin include inhib......

MicroRNA-185 induces potent autophagy via AKT signaling in hepatocellular carcinoma

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Studies have demonstrated that microRNA 185 may be a promising therapeutic target in liver cancer. However, its role in hepatocellular carcinoma is la......

Downregulated XPA promotes carcinogenesis of bladder cancer via impairment of DNA repair

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Bladder cancer is the most common malignant tumor of urinary system, largely resulting from failure of repair of DNA damage to the environmental insul......

miR-29a suppresses MCF-7 cell growth by downregulating tumor necrosis factor receptor 1

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Tumor necrosis factor receptor 1 is the main receptor mediating many tumor necrosis factor-alpha-induced cellular events. Some studies have shown that......

Overexpression of junctional adhesion molecule-A and EphB2 predicts poor survival in lung adenocarcinoma patients

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Junctional adhesion molecules are important components of tight junctions, and Eph/ephrin proteins constitute the largest family of receptor tyrosine ......

Beta-1,4-galactosyltransferase II predicts poor prognosis of patients with non-metastatic clear-cell renal cell carcinoma

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Beta-1,4-galactosyltransferase II is found to be associated with the alterations of tumor-related glycosylation. However, the clinical significance of......

MicroRNA-223-3p inhibits human bladder cancer cell migration and invasion

期刊: TUMOR BIOLOGY, 2017; 39 (2)

The regulation of initiation and progression during carcinogenesis of bladder carcinoma is not completely elucidated. Dysregulation of microRNAs has b......

MicroRNAs regulate the epithelial-mesenchymal transition and influence breast cancer invasion and metastasis

期刊: TUMOR BIOLOGY, 2017; 39 (2)

MicroRNAs are small RNA molecules that play a major role in the post-transcriptional regulation of genes and influence the development, differentiatio......

LDOC1 regulates Wnt5a expression and osteosarcoma cell metastasis and is correlated with the survival of osteosarcoma patients

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Osteosarcomas are common bone malignancies in children and adolescents. LDOC1 (leucine zipper, down-regulated in cancer 1), a tumor suppressor, is dow......

MiR-122 promotes renal cancer cell proliferation by targeting Sprouty2

期刊: TUMOR BIOLOGY, 2017; 39 (2)

MicroRNAs are short non-coding RNAs, which have been implicated in several biological processes. Aberrant expression of the microRNA miR-122 has frequ......

Orail mediates tumor-promoting store-operated Ca2+ entry in human gastrointestinal stromal tumors via c-KIT and the extracellular signal-regulated kinase pathway

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Gastrointestinal stromal tumors originate from interstitial cells of Cajal, the pacemaker cells of the gut. Ca2+ regulates the pacemaker activity of i......

Increased Eps15 homology domain 1 and RAB11FIP3 expression regulate breast cancer progression via promoting epithelial growth factor receptor recycling

期刊: TUMOR BIOLOGY, 2017; 39 (2)

Recent research indicates that the C-terminal Eps15 homology domain 1 is associated with epithelial growth factor receptor-mediated endocytosis recycl......

Dynamic tracing for epidermal growth factor receptor mutations in urinary circulating DNA in gastric cancer patients

期刊: TUMOR BIOLOGY, 2017; 39 (2)

The mutations of epidermal growth factor receptor are detected in gastric cancer, indicating its suitability as a target for receptor tyrosine kinase ......

Comprehensive profiling and quantitation of oncogenic mutations in non-small cell lung carcinoma using single-molecule amplification and re-sequencing technology

期刊: TUMOR BIOLOGY, 2017; 39 (2)

The carcinogenesis of non-small cell lung carcinoma has been found to associate with activating and resistant mutations in the tyrosine kinase domain ......

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