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MicroRNA-139-5p inhibits inflammatory and oxidative stress responses of Salmonella-infected macrophages through modulating TRAF6

期刊: PATHOGENS AND DISEASE, 2021; 79 (4)

Evidence indicates that macrophages play an important role in the immune system. Therefore, research involving inflammatory and oxidative stress respo......

Insights into the biomarkers of viral encephalitis from clinical patients

期刊: PATHOGENS AND DISEASE, 2021; 79 (1)

Background: biomarkers can be helpful in identifying patients who may profit by explicit treatments or evaluating the reaction to the treatment of spe......

Exacerbation of disease by intranasal liquid administration following influenza virus infection in mice

期刊: PATHOGENS AND DISEASE, 2020; 78 (2)

Although numerous studies have clarified the synergistic pathogenesis in mouse models of influenza A virus (IAV)-associated dual infections, fewer stu......

Bacillus subtilis RZ001 improves intestinal integrity and alleviates colitis by inhibiting the Notch signalling pathway and activating ATOH-1

期刊: PATHOGENS AND DISEASE, 2020; 78 (2)

Intestinal mucosal barriers help the body resist many intestinal inflammatory diseases, such as inflammatory bowel disease (IBD). In this study, we id......

The pathological autopsy of coronavirus disease 2019 (COVID-2019) in China: a review

期刊: PATHOGENS AND DISEASE, 2020; 78 (3)

The coronavirus disease 2019 (COVID-2019) that emerged in Wuhan, China, has rapidly spread to many countries across all six WHO regions. However, its ......

Rhinovirus impairs the immune response of alveolar macrophages to facilitate Streptococcus pneumonia infection

期刊: PATHOGENS AND DISEASE, 2020; 78 (3)

Pneumonia is one important cause of mortality in neonates. However, the mechanism remains still unclear. Viral infection greatly enhances the morbidit......

Positive SARS-CoV-2 RNA recurs repeatedly in a case recovered from COVID-19: dynamic results from 108 days of follow-up

期刊: PATHOGENS AND DISEASE, 2020; 78 (4)

The evidence of long-term clinical dynamic on Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) RNA re-positive case are less. We performed......

Transcriptome-based drug repositioning for coronavirus disease 2019 (COVID-19)

期刊: PATHOGENS AND DISEASE, 2020; 78 (4)

The outbreak of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) around the world has led to a pandemic with high morbidity and mortality.......

GlgA plays an important role in the induction of hydrosalpinx by Chlamydia muridarum

期刊: PATHOGENS AND DISEASE, 2020; 78 (4)

While glycogen synthase A deficiency can reduce the growth and proliferation of Chlamydia muridarum, the effect of glycogen synthase A on the pathogen......

Hyperglycemia suppresses the regulatory effect of hypoxia-inducible factor-1 alpha in pulmonary Aspergillus fumigatus infection

期刊: PATHOGENS AND DISEASE, 2020; 78 (5)

Aspergillus fumigatus is one of the most common fungal infections involved in the pulmonary diseases. Hypoxia-inducible factor-1 alpha (HIF-1 alpha) i......

Hepatic dysfunction induced by intestinal dysbacteriosis mainly manifests as immunologic abnormity in mice

期刊: PATHOGENS AND DISEASE, 2020; 78 (6)

Currently, the potential role of the alterations occurring in the liver immune system and intestinal flora in liver injury remains unknown. Our study ......

Berberine functions as a negative regulator in lipopolysaccharide -induced sepsis by suppressing NF-kappa B and IL-6 mediated STAT3 activation

期刊: PATHOGENS AND DISEASE, 2020; 78 (7)

Sepsis is a deadly complication raised by bacterial pathogens-induced dysregulated innate inflammatory response. Thus, anti-inflammatory is a potentia......

NIK inhibitor impairs chronic periodontitis via suppressing non-canonical NF-kappa B and osteoclastogenesis

期刊: PATHOGENS AND DISEASE, 2020; 78 (7)

Periodontitis is an inflammatory disease that causes damages to periodontium and alveolar bone. Overactivation and formation of osteoclasts can cause ......

Accumulation of EBI3 induced by virulent Mycobacterium tuberculosis inhibits apoptosis in murine macrophages

期刊: PATHOGENS AND DISEASE, 2019; 77 (1)

Macrophages are the primary host target cells of Mycobacterium tuberculosis (M. tb). As a subunit of immunoregulatory cytokines IL-27 and IL-35, Epste......

JIF:2.18

Intestinal dysbiosis promotes epithelial-mesenchymal transition by activating tumor-associated macrophages in ovarian cancer

期刊: PATHOGENS AND DISEASE, 2019; 77 (2)

We aimed to investigate the relationship of intestinal dysbiosis (IDB) and ovarian cancer progression, and understand its underlying signaling mechani......

JIF:2.18

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