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Reg3 beta: A Potential Therapeutic Target for Tissue Injury and Inflammation-Associated Disorders

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, ; ()

Since regenerating islet-derived 3 beta (Reg3 beta) was first reported, various studies have been conducted to explore the involvement of Reg3 beta in......

Immune checkpoints in sepsis: New hopes and challenges

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, ; ()

Sepsis is a life-threatening syndrome with a high incidence and a weighty economic burden. The cytokines storm in the early stage and the state of imm......

Cytokine release syndrome in COVID-19: a major mechanism of morbidity and mortality

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, ; ()

The coronavirus disease 2019 (COVID-19) triggered by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) erupted in Hubei Province of China i......

BCG-induced trained immunity in macrophage: reprograming of glucose metabolism BCG-induced trained immunity by enhanced glycolysis and glutamine-driven tricarboxylic acid cycle in macrophage

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2020; 39 (3)

Memory is no longer a privilege of adaptive immunity. Innate immune cells can exhibit a long-term immune activation after infection or vaccination, wh......

Contribution of mouse models in our understanding of lupus

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2020; 39 (4)

Laboratory animal models are beneficial when they recapitulate all or just some of the clinical and immunological manifestations of the disease. Vario......

Reactive oxygen species and immune regulation

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2020; 39 (6)

Reactive oxygen species (ROS) is a kind of single electron reduction product of oxygen in vivo. Because they contain unpaired electrons, ROS has high ......

Pregnancy immune tolerance at the maternal-fetal interface

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2020; 39 (6)

Pregnancy is a natural process that poses an immunological challenge because non-self fetus must be accepted. During the pregnancy period, the fetus a......

The role of pro-inflammatory cytokines in lipid metabolism of metabolic diseases

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2019; 38 (6)

Adipose tissue has been considered as a crucial source of certain pro-inflammatory cytokines; conversely, these pro-inflammatory cytokines are involve......

JIF:3.48

Chicken toll-like receptors and their significance in immune response and disease resistance

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2019; 38 (6)

Infectious diseases are a major challenge for the poultry industry that causes widespread production losses. Thus, management and control of poultry h......

JIF:3.48

Microbiota regulate the development and function of the immune cells

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2018; 37 (2)

Microbiota is a group of microbes coexisting and co-evolving with the immune system in the host body for millions of years. There are mutual interacti......

JIF:3.48

MicroRNA-22-3p as a novel regulator and therapeutic target for autoimmune diseases

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2017; 36 (3)

MicroRNAs (miRNAs) are a class of noncoding RNAs and have emerged as critical regulators of gene expression. Some miRNAs play important roles in regul......

JIF:2.93

Multiple functions of the E3 ubiquitin ligase CHIP in immunity

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2017; 36 (5)

The carboxyl terminal of Hsp70-interacting protein (CHIP) is an E3 ubiquitin ligase that plays a pivotal role in the protein quality control system by......

JIF:2.93

The mechanisms of IL-17A on promoting tumor metastasis

期刊: INTERNATIONAL REVIEWS OF IMMUNOLOGY, 2017; 36 (6)

In recent decades, extensive studies have indicated that IL-17A plays an important role in tumor progression and metastasis, but the underlying mechan......

JIF:2.93

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