期刊： ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2020; 37 (3)
There are currently no skin sensitization assays based on T cell activation. We built a novel in vitro test to assess T cell activation and assessed i......
期刊： ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2020; 37 (3)
The first microfluidic microphysiological systems (MPS) entered the academic scene more than 15 years ago and were considered an enabling technology t......
期刊： ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2020; 37 (2)
Rheumatoid arthritis (RA) is a chronic systemic autoimmune inflammatory disease characterized by progressive bone and cartilage destruction, functiona......
期刊： ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2020; 37 (2)
Reduction of animal suffering during in vivo experiments is usually ensured by continuously monitoring the health status using a score sheet and by ap......
期刊： ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2019; 36 (3)
To more accurately model inhalation toxicity in vitro, we developed a tetra-culture system that combines lung alveolar epithelial cells, endothelial c......
期刊： ALTEX-ALTERNATIVES TO ANIMAL EXPERIMENTATION, 2019; 36 (3)
Since the EU banned animal testing for cosmetic products and ingredients in 2013, many defined approaches (DA) for skin sensitization assessment have ......
