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STAT4 regulates cardiomyocyte apoptosis in rat models of diabetic cardiomyopathy

期刊: ACTA HISTOCHEMICA, 2022; 124 (4)

Objective: This study aimed to investigate the protective role of the signal transducer and activator of transcription 4 (STAT4) in diabetic cardiomyo......

JIF:2.258

Induced neural stem cells from Macaca fascicularis show potential of dopaminergic neuron specification and efficacy in a mouse Parkinson?s disease model

期刊: ACTA HISTOCHEMICA, 2022; 124 (6)

Induced neural stem cells (iNSCs) can be reprogrammed from somatic cells and have shown potentials in treatment of various neurological diseases/disor......

JIF:2.258

The raft cytoskeleton binding protein complexes personate functional regulators in cell behaviors

期刊: ACTA HISTOCHEMICA, 2022; 124 (2)

Several cytoskeleton proteins interact with raft proteins to form raft-cytoskeleton binding protein complexes (RCPCs) that control cell migration and ......

JIF:2.258

Bmal1 promotes cementoblast differentiation and cementum mineralization via Wnt/beta-catenin signaling

期刊: ACTA HISTOCHEMICA, 2022; 124 (3)

Remodeling of the cementum plays a crucial role in periodontal regenerative therapy, while the precise mech-anism of cementogenesis has yet been adequ......

JIF:2.258

Vaspin contributes to autophagy and endothelial-to-mesenchymal transition via PI3K-/AKT-mTOR pathway

期刊: ACTA HISTOCHEMICA, 2022; 124 (4)

Background: Visceral adipose tissue-derived serine protease inhibitor (Vaspin) was found to have antiinflammatory, anti-apoptosis, and pro-autophagy a......

JIF:2.258

Fibroblast-derived exosomal miRNA-133 promotes cardiomyocyte-like differentiation

期刊: ACTA HISTOCHEMICA, 2022; 124 (6)

Objective: To investigate the role of exosomal miRNA-133 secreted by cardiac fibroblasts (CFs) in promoting cardiomyocyte differentiation. Methods: Ne......

JIF:2.258

Inhibition of glutamine transporter ASCT2 mitigates bleomycin-induced pulmonary fibrosis in mice

期刊: ACTA HISTOCHEMICA, 2022; 124 (8)

Background: Idiopathic pulmonary fibrosis (IPF) represents a fatal pulmonary disease. Its mechanisms remain unclear and effective therapies are urgent......

JIF:2.258

Drp1 knockdown represses apoptosis of rat retinal endothelial cells by inhibiting mitophagy

期刊: ACTA HISTOCHEMICA, 2022; 124 (1)

Diabetic retinopathy (DR) is the leading clinical cause of blindness in diabetic patients. Mitophagy participates in the pathogenesis of DR. Dynamin r......

JIF:2.258

The role of KLF4 in melanogenesis and homeostasis in sheep melanocytes

期刊: ACTA HISTOCHEMICA, 2022; 124 (1)

KLF4 expression has been associated with hair color in mammals and has also been found to regulate melanoma cell growth. Here, we assessed the influen......

JIF:2.258

Sensitizing TRAIL response via differential modulation of anti- and pro-apoptotic factors by AZD5582 combined with ER nanosomal TRAIL in neuroblastoma

期刊: ACTA HISTOCHEMICA, 2022; 124 (2)

Neuroblastoma is a metastatic brain tumor particularly common in children. The cure rate is below 50% for patients of high-risk condition. Novel thera......

JIF:2.258

A ?selective secondary tissue attachment? method for isolation and purification of mammary epithelial cells

期刊: ACTA HISTOCHEMICA, 2022; 124 (8)

Background: Mammary epithelial cells (MECs) are specific target cells to study the underlying mechanism for mammary gland development and lactation, m......

JIF:2.258

microRNA-25-3p suppresses osteogenic differentiation of BMSCs in patients with ITGB3

期刊: ACTA HISTOCHEMICA, 2022; 124 (6)

This study was conducted to investigate the impact of the microRNA (miR)-25-3p/ITGB3 axis on the osteogenic differentiation of bone marrow mesenchymal......

JIF:2.258

Calycosin alleviates hyperbilirubin nerve injury in Ugt1(-/-) mice by inhibiting oxidative stress, apoptosis, and mitochondrial function

期刊: ACTA HISTOCHEMICA, 2022; 124 (6)

Background and purpose: Hyperbilirubinemia is a common condition in neonates that is associated with poor neurodevelopmental outcomes. Although studie......

JIF:2.258

microRNA-146a mediates distraction osteogenesis via bone mesenchymal stem cell inflammatory response

期刊: ACTA HISTOCHEMICA, 2022; 124 (6)

Distraction osteogenesis (DO) is a widely used surgical technique to repair bone defects, partly owing to its high efficiency in inducing osteogenesis......

JIF:2.258

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